Allergy, Asthma, Immunology & Rheumatology

University Pediatricians | Michigan

About the Division of Allergy, Asthma, Immunology and Rheumatology

The Allergy, Asthma, Immunology and Rheumatology Division at the Children’s Hospital of Michigan has a long history of excellence in the care of patients with asthma, allergies, immunodeficiencies, autoimmune and rheumatologic diseases.

The focus of the Allergy, Asthma, Immunology and Rheumatology Division at the Children’s Hospital of Michigan is to:

  • Provide compassionate, state-of-the-art diagnosis and treatment for patients of all age with allergic and immunologic diseases, including asthma, and children with autoimmune and rheumatologic diseases.
  • Train physicians for academic careers in allergy, asthma, and immunology or subspecialty clinical practice.
  • Promote and conduct basic, clinical, and translational research in allergy, asthma, clinical immunology and rheumatology.
  • Be a local, regional, and national source for the specialty and collaborate with others  to expand and share knowledge in allergy, asthma, clinical immunology, and pediatric rheumatology.

Leadership

The Chief of Allergy, Asthma, Immunology and Rheumatology Division, Pavadee Poowuttikul, MD, along with six board certified allergists/immunologists and two board certified pediatric rheumatologist, all have faculty appointments at Central Michigan University College of Medicine. All faculty are actively involved in teaching medical students from Central Michigan University and Wayne State University, pediatric and internal medicine residents, and allergy/immunology fellows. The division also includes specialized allergy/immunology/rheumatology nurse practitioners, nurses, and social workers.

Allergy, Asthma, Immunology and Rheumatology Clinical Programs

The Asthma, Allergy and Immunology Section treats children and adults with allergic disorders and asthma. We offer evaluation, treatment and participation in research studies for patients with asthma and a wide range of allergies, including food allergy, environmental allergy, drug allergy, insect sting allergy, angioedema, anaphylaxis, hives, eczema, and other allergic skin conditions. In office pulmonary function testing, FeNO testing and allergy skin tests can be completed during a clinic visit. Advanced treatment plans are available for specific conditions including allergen immunotherapy, oral immunotherapy for food allergy, and monoclonal antibody treatment for food allergy, asthma, and atopic dermatitis.


The Immunology Section offers a Primary Immune Deficiency Clinic for children and adults. Primary and secondary immune deficiency disorders evaluated and treated include: agammaglobulinemia, specific antibody deficiency, common variable immune deficiency, IgA deficiency, hyper IgE syndrome, hyper lgM syndrome, chronic granulomatous disease, severe combined immune deficiency, Wiskott–Aldrich syndrome, Mendelian susceptibility to mycobacterial diseases, Chronic Mucocutaneous Candidiasis and 22q11.2 deletion syndromes. We also serve as a diagnostic and referral center for patients with complex medical conditions involving the immune system. The division is the coordination center for the Primary Immunodeficiency Newborn Screening Center for the State of Michigan.


The Pediatric Rheumatology Section offers a rheumatology clinic and vasculitis clinic for children and adolescents. Conditions evaluated and treated include childhood autoimmune diseases such as juvenile idiopathic arthritis, systemic lupus erythematosus, vasculitis and juvenile dermatomyositis; and autoinflammatory disorders such as periodic fever syndromes, and autoinflammatory disorders of the bones. 


Our faculty are familiar with the most recent advances and recommendations in the management of allergic, immunologic, and rheumatologic conditions and offer comprehensive and patient-centered services geared towards their diagnosis and treatment. The team of dedicated nurses work on obtaining prior authorizations for expensive medications deemed necessary for management of the patients in order to provide them the most cost-effective therapy. Outpatient appointments are available Monday-Friday and some Saturdays. Same-day appointments are available for patients requiring urgent evaluations.

Our specialized clinics include:

  • Drug Allergy Procedures Clinic:

    Only about 10% of patients who believe they are allergic to penicillin truly are. Labeling patients “allergic” when they are not can cause a burden both for patients and our health care system. Patients may not be able to get a first-line drug for treatment, leading to the use of more expensive antibiotics, and the risk of developing antibiotic resistant infections.


    We offer a Drug Allergy Procedures Clinic focused on testing for drug allergies. Patients will have an initial evaluation to determine if the test and/or challenges are appropriate and will be referred to the Drug Allergy Procedures Clinic if needed. In this clinic, patients will either complete extensive allergy skin testing, undergo a direct oral challenge or both, under close supervision. Following a period of observation, the patient’s drug allergy will either be confirmed or can be safely removed from the allergy list.


    We also provide an evaluation for aspirin allergy and aspirin desensitization for patients with Aspirin-Exacerbated Respiratory Disease (AERD). Other medication challenges are also possible depending on the types of the reactions. Venom testing for patients with an insect sting allergy is also available.

  • Food Challenge Clinic:

    Food allergies affect 5.6 million children in the U.S. Symptoms of food allergy range from mild to life threatening. Many children will outgrow a food allergy. The Allergy and Immunology Division at Children’s Hospital of Michigan helps patients find out if they have outgrown a food allergy or if the patient is truly allergic to certain foods. Once the patient is evaluated during the initial clinic visit and determined that an oral food challenge is indicated, the patient will be referred to the Food Challenge Clinic. During the Food Challenge Clinic, the reintroduction of the food will be performed under close monitoring. Each oral food challenge appointment takes approximately four hours, as the food will be introduced gradually. A successful food challenge confirms that the patient has outgrown the food allergy and the food can be safely reintroduced into their regular diet. While allergy testing alone can fail to define food tolerance, oral food challenges provide an effective and definitive way to rule out food allergy. We also perform evaluation and early introduction of peanuts to infants who may be at high risk. Peanut-allergic patients, who are qualified for peanut oral immunotherapy (OIT), will be offered this therapy and receive their initial doses of peanut in the Food Challenge Clinic as well.

  • High-Risk Asthma Clinic:

    The high-risk asthma clinic offers comprehensive medical and psychosocial support to children with severe, difficult-to-control and/or high-risk asthma. Research studies with an emphasis on adherence to medication and identification of stressors are available to patients with asthma and interested families. The program involves a multidisciplinary team, including asthma/allergy specialist, asthma nurse educator, and social worker, that assists in addressing treatment barriers and comorbid conditions that can contribute to asthma severity. We take a patient centered approach to improve asthma control and the quality of life of our patients and families with particular emphasis on follow-up, daily care, asthma control, asthma education, and action planning. Our goal is to work with families to help minimize the effect of asthma on children by creating detailed treatment plans to prevent symptoms, to identify and prevent asthma triggers, and to create response plans to treat asthma flare-ups.

  • Primary Immunodeficiency Clinic:

    At Children’s Hospital of Michigan, our Immunodeficiency Clinic provides diagnostic and treatment services for children and adults with suspected or known primary or secondary immunodeficiency disorders. We serve as a referral center to help families and physicians in the evaluation and care of individuals with immunodeficiency disorders. Our program is one of the three coordination centers for the severe combined immune deficiency screening program for the State of Michigan. Our multidisciplinary team includes a clinical immunologist, immunology nurse educator, and social worker, and offers comprehensive medical and psychosocial support and resources to patients with immunodeficiency and their families. We work closely with infectious disease specialists and Hematology/Oncology Transplant medicine specialists to provide access to the latest treatment options. Our program is a member of the United States Immunodeficiency Network (USIDNET) and Immunodeficiency Foundation (IDF). We welcome the opportunity to provide a second opinion on the diagnosis and/or treatment plan for primary immunodeficiency disorders.

  • Vasculitis Clinic:

    Systemic vasculitis in children is a complex group of diseases affecting multiple organ systems. Comprehensive care may require coordinated treatment across multiple specialties including pediatric rheumatology and pediatric nephrology. The Vasculitis Clinic at Children’s Hospital of Michigan is a cooperative effort of physicians to allow the patient to see both specialists in a single visit for ease of collaboration onsite, and to form a care plan that encompasses all aspects of this complex group of diseases.

Appointments with the Allergy, Asthma and Immunology experts are available at five convenient Children's Hospital of Michigan locations throughout the metropolitan area listed below. Pediatric Rheumatology appointments are available at Children's Hospital of Michigan Specialty Center – Detroit and Troy location. Families can call 313-745-KIDS or 313-832-8550 to schedule an appointment.

Faculty

Faculty


Advanced Practice Providers

Want to learn more about our distinguished specialists? Click the button below to be taken to our Faculty Directory.

Faculty Directory →

Education

At the Children’s Hospital of Michigan, our goals are to prepare our fellows to pursue future careers in academic medicine or subspecialty clinical practice and to qualify for the American Board of Allergy and Immunology. The program is ACGME accredited and offers comprehensive, balanced clinical training in allergy/immunology in both adults and pediatric patients, with emphasis on evaluation and management of allergic disorders, asthma and primary immunodeficiency disorders. We prepare our fellows for a strong foundation in the basic and clinical immunology important to understanding and managing allergic/immunologic disorders.


The institution is a major pediatric tertiary referral center and is the coordinating center for the Severe Combined Immune Deficiency Newborn Screening Program for the State of Michigan. Fellows gain additional experience in dedicated clinics for inner-city asthma, eosinophilic esophagitis, and primary immunodeficiency disorders with specialized nursing staff and social workers. Elective rotations in ENT, dermatology, rheumatology, pulmonology, and infectious disease are available in both adult and pediatric specialties. Other elective rotations include clinical immunology laboratory and allergen extract preparation. Fellows will be proficient in allergen immunotherapy, monoclonal antibody treatments, immunoglobulin replacement therapy, and other treatment modalities available for primary immunodeficiency disorders.


Fellows will learn to design and conduct allergy and/or immunology research under the supervision of research mentor(s) who are fellowship program faculty. Research resources are available through the Children’s Research Institute of Michigan and the Children’s Hospital Foundation. Fellow research projects are involved in QI, translational, and clinical research. Fellows are expected to present their research at national meetings and in peer-reviewed publications.


For more information, please refer to the Allergy/Immunology Fellowship Training Website—click here or on the button below to visit the site.

Allergy/Immunology Fellowships →

  • Trainees Accepted Each Year

    1 per year

  • Duration of Fellowship

    2 years

  • Number of Graduates Last 5 Years, and Subsequent Career Choice

    2018-2023

    8 graduates (5 academic, 3 private practice)

  • Application Deadline

    Please refer to the National Resident Matching Program (NRMP) website for fellowship match information in regards to the fellowship timeline, application deadlines and additional important dates.

  • Electives for Residents and Students

    Yes

  • Special Requirements

    ABIM or ABP eligible or certified

  • Program Information and Contacts

    Division of Allergy, Immunology, and Rheumatology

    Children's Hospital of Michigan

    3950 Beaubien Blvd.

    Detroit, MI 48201


    Phone: (313) 745-5751 and (313) 832-8506

    Fax: (313) 993-7118

    Email: ppoowutt@dmc.org


    Program Website: https://www.childrensdmc.org/health-professionals/just-for-doctors/fellowships/allergy-immunology


    Program Director

    Pavadee Poowuttikul, MD

    Phone: (313) 745-5751, (313) 832-8506

    Email: ppoowutt@dmc.org


    Associate Program Director

    Jenny Huang, MD

    Phone: (313) 832-8550

    Email: jhuang2@dmc.org


    Program Coordinator

    Dionne Weathers

    Pediatric Graduate Medical Education

    Phone:  313-745-5751

    313-832-8506 Specialty Center

    Email: Dweather@dmc.org

    Fax: 313-993-7118

Research

Our faculty and fellows are committed to research involving the diagnosis and management of patients with inner-city asthma, primary and secondary immunodeficiency diseases, autoimmune, rheumatologic, and other immunologic diseases, food allergies and other atopic disorders through basic, translational, and clinical research.

Our active clinical research trials/projects include:

  • The Use of an Electronic Monitoring Device for Wheezing (Wheezo) and a Remote Monitoring Program (RMP) to Improve Asthma Outcomes in Inner-City Children
  • Extent of Immunosuppression from Oral Steroid Bursts in Inner-City Asthma Children
  • The Evaluation of Treatment and Outcomes in Patients with Eosinophilic Esophagitis
  • Clinical Markers for Likelihood of Admission to Pediatric Intensive care unit (PICU) due to Anaphylaxis
  • Anaphylaxis and Asthma Education in Schools
  • Predictors for Low TRECs in infants without SCID or severe thymic defects
  • Outcomes of TREC based SCID Newborn Screening in Michigan: 10-year data
  • Geomapping High-Risk Zip codes in Detroit for social determinants of health
  • Risk Factors Associated with Poor Asthma Control Utilizing National Dataset
  • A Randomized, Double-blind, Multicenter, Parallel-group, Phase IIIb 52 Week Study Evaluating the Efficacy and Safety of PT027 Compared with PT007 Administered As Needed in Participants 12 to < 18 Years of Age with Asthma (ACADIA)
  • A Validation Study of the Pediatric Asthma Impairment and Risk Questionnaire (AIRQ)
  • A Multicentre, Randomized, Double-Blind, Parallel-Group Placebo-Controlled, Phase 3, Efficacy and Safety Study of Tezepelumab in 5 to <12 Year Old Children with Severe Uncontrolled Asthma (HORIZON)
  • Penicillin de-labeling program
  • Asthma in-patient discharge quality improvement project
  • Evaluation for post-transplant secondary immunodeficiency
  • Evaluation for secondary immunodeficiency with immunosuppressive medications
  • The Impact of Food Insecurity in Food Allergic Populations
  • Inpatient community health worker program for poorly controlled pediatric asthma

Recent Faculty Publications

  • Marwa El-Bohy

    • El-Bohy M, Poowuttikul P, Secord E. Humoral Immune Deficiencies of Childhood. Immunol Allergy Clin North Am. 2021 Nov;41(4):527-533. doi: 10.1016/j.iac.2021.07.004. PMID: 34602225.
    • El-Bohy M, Poowuttikul P, Secord E. Humoral Immune Deficiencies of Childhood. Pediatr Clin North Am. 2019 Oct;66(5):897-903. doi: 10.1016/j.pcl.2019.06.010. PMID: 31466679.

  • Basil Fathalla, MD

    • Fathalla BM, Elgabaly EA, Tayoun AA. Coexistence of a novel WISP3 pathogenic variant and an MEFV mutation in an Arabic family with progressive pseudorheumatoid dysplasia mimicking polyarticular juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2020 Sep 7;18(1):69.
    • Kashyape P, D'Souza AP, Fathalla B. En coup de sabre presenting as status epilepticus. Clin Rheumatol. 2020 Dec; 39(12):3885-3886.
    • Mathew A, Abuhammour W, Fathalla B, Otour B. Parvovirus B19 Infection Mimicking Juvenile Myelomonocytic Leukemia in an Immunocompetent Child. Cureus. 2020 Jun 26;12(6):e8854.
    • Mahfouz NA, Kizhakkedath P, Ibrahim A, El Naofal M, Ramaswamy S, Harilal D, Qutub Y, Uddin M, Taylor A, Alloub Z, AlBanna A, Abuhammour W, Fathalla B, Tayoun AA. Utility of clinical exome sequencing in a complex Emirati pediatric cohort. Comput Struct Biotechnol J. 2020 Apr 22;18:1020-1027.
    • Al-Mayouf SM, Almutairi A, Albrawi S, Fathalla BM, Alzyoud R, AlEnazi A, Abu-Shukair M, Alwahadneh A, Alsonbul A, Zlenti M, Khawaja E, Abushhaiwia A, Khawaja K, AlMosawi Z, Madan W, Almuatiri M, Almuatiri N; for Pediatric Arab Rheumatology Group (PRAG). Pattern and diagnostic evaluation of systemic autoinflammatory diseases other than familial Mediterranean fever among Arab children: a multicenter study from the Pediatric Rheumatology Arab Group (PRAG). Rheumatol Int. 2020 Jan;40(1):49-56.

  • Jenny Huang, MD

    • Huang J, Shankar A, Hurden I, et al. Increased mortality in infants with abnormal T-cell receptor excision circles. Pediatr Res. Published online March 5, 2024. doi:10.1038/s41390-024-03121-7
    • Mongkonsritragoon, W, Huang, J, Fredrickson, M, Seth, D, Poowuttikul, P. Positive Newborn Screening for Severe Combined Immunodeficiency: What Should the Pediatrician Do?. Clin Med Insights Pediatr. 2023; 17. 37025258. 10.1177/11795565231162839
    • Mongkonsritragoon, W, Prueksapraoprong, C, Kewcharoen, J, Tokavanich, N, Prasitlumkum, N, Huang, J, Poowuttikul, P. Prevalence and risk associated with asthma in children hospitalized with SARS-CoV-2: a meta-analysis and systematic review. J Allergy Clin Immunol Pract. 2022; 10(5): 1382-1384.e1. 35123100. 10.1016/j.jaip.2021.12.044
    • Huang J, Kaur B, Farooqi A, et al. Elevated Glycated Hemoglobin Is Associated with Reduced Antibody Responses to Vaccinations in Children. Pediatr Allergy Immunol Pulmonol. 2020;33(4):193-198. doi:10.1089/ped.2020.1160

  • Aishwarya Navalpakam

    • Navalpakam A, Thanaputkaiporn N, Aijja C, et al. Impact of steroids on the immune profiles of children with asthma living in the inner-city. Allergy Asthma Proc. 2024;45(2):100-107. doi:10.2500/aap.2024.45.230090
    • Navalpakam A, Thanaputkaiporn N, Poowuttikul P. Anaphylaxis: Long-term management and resources. Allergy Asthma Proc. 2023;44(1):35-44. doi:10.2500/aap.2023.44.220089
    • Mongkonsritragoon W, Srivastava R, Seth D, Navalpakam A, Poowuttikul P. Non-infectious Pulmonary Complications in Children with Primary Immunodeficiency. Clin Med Insights Pediatr. 2023;17:11795565231196431. Published 2023 Sep 8. doi:10.1177/11795565231196431
    • Navalpakam A, Thanaputkaiporn N, Poowuttikul P. Management of Anaphylaxis. Immunol Allergy Clin North Am. 2022;42(1):65-76. doi:10.1016/j.iac.2021.09.005
    • Navalpakam A, Secord E, Pansare M. The Impact of Coronavirus Disease 2019 on Pediatric Asthma in the United States. Pediatr Clin North Am. 2021;68(5):1119-1131. doi:10.1016/j.pcl.2021.05.012

  • Milind Pansare, MD

    • Alrayes T, Shihan H, Smith-Dewey R, et al. Enlarging Nasal Cavity Mass in a Young Adolescent Male. Clin Pediatr (Phila). 2023;62(1):68-72. doi:10.1177/00099228221110957
    • Pansare M, Seth D, Kamat A, Kamat D. Summer Buzz: All You Need to Know about Insect Sting Allergies. Pediatrics in Review, Jul 2020, 41 (7) 348-356
    • Saini S, Pansare M. New Insights and Treatments in Atopic Dermatitis. Immunol Allergy Clin North Am. 2021;41(4):653-665. doi:10.1016/j.iac.2021.07.005

  • Pavadee Poowuttikul, MD

    • Navalpakam A, Thanaputkaiporn N, Aijja C, et al. Impact of steroids on the immune profiles of children with asthma living in the inner-city. Allergy Asthma Proc. 2024;45(2):100-107. doi:10.2500/aap.2024.45.230090
    • Navalpakam A, Thanaputkaiporn N, Poowuttikul P. Anaphylaxis: Long-term management and resources. Allergy Asthma Proc. 2023;44(1):35-44. doi:10.2500/aap.2023.44.220089
    • Mongkonsritragoon, W., Prueksapraoprong, C., Kewcharoen, J., Tokavanich, N., Prasitlumkum, N., Huang, J., Poowuttikul, P. Prevalence and Risk associated with Asthma in Children hospitalized with SARS-CoV-2: A Meta-analysis and Systematic review. [published online ahead of print, 2022 Feb 2]. J Allergy Clin Immunol Pract. 2022 May;10(5):1382-1384.e1. doi: 10.1016/j.jaip.2021.12.044. Epub 2022 Feb 2. 
    • Secord, E., Poowuttikul, P., Hoofman, J., Arsenault, S. Sustained Decrease in Pediatric Asthma Emergency Visits During the First Year of COVID-19 Pandemic. Allergy Asthma Proc. 2021;42(5):400-402. doi:10.2500/aap.2021.42.210059
    • Alvarez, A., Gupta, M., Poowuttikul, P., Baptist, A. Are primary care physicians following National Institute of Allergy and Infectious Disease guidelines for the prevention of peanut allergy? A survey-based study. Allergy Asthma Proc. 2020 May 1;41(3):167-171. doi: 10.2500/aap.2020.41.200019. PMID: 32375960
    • Darian, T., Freij, J., Seth, D., Poowuttikul, P., Secord, E. A Review of Primary Immune Deficiency Disorders. EMJ Allergy Immunol. 2020;5[1]:70-77.
    • Poowuttikul, P., Seth, D. New Concepts and Technological Resources in Patient Education and Asthma Self-Management. Clin Rev Allergy Immunol. 2020 Mar 25. doi: 10.1007/s12016-020-08782-w. Review. PMID: 32215784
    • Huang J, Kaur B, Farooqi A, et al. Elevated Glycated Hemoglobin Is Associated with Reduced Antibody Responses to Vaccinations in Children. Pediatr Allergy Immunol Pulmonol. 2020;33(4):193-198. doi:10.1089/ped.2020.1160
    • Seth, D., Poowuttikul, P., Pansare, M., Kamat, D. Food Allergy: A Review. Pediatr Ann. 2020;49(1):e50-e58. doi:10.3928/19382359-20191206-01. PMID: 31930423

  • Divya Seth, MD

    • Huang J, Shankar A, Hurden I, Thomas R, Hill J, Seth D, Secord E, Poowuttikul P. Increased mortality in infants with abnormal T-cell receptor excision circles. Pediatr Res. Published online March 5, 2024. doi:10.1038/s41390-024-03121-7
    • Mongkonsritragoon W, Srivastava R, Seth D, Navalpakam A, Poowuttikul P. Non-infectious Pulmonary Complications in Children with Primary Immunodeficiency. Clin Med Insights Pediatr. 2023;17:11795565231196431. Published 2023 Sep 8. doi:10.1177/11795565231196431
    • Seth D, Poowutikul P, Pansare M, Kamat D. Food Allergy: A Review. Pediatr Ann. 2020; 49(1):e50-e58. PMID: 31930423. 
    • Poowuttikul P, Seth D. New Concepts and Technological Resources in Patient Education and Asthma Self-Management. Clinical Reviews in Allergy & Immunology 2020; 59(1):19-37 
    • Darian T, Freij JB, Seth D, Poowuttikul P, Secord E. EMJ Allergy Immunol. 2020; 5(1): 70-77. 
    • Pansare M, Seth D, Kamat A, Kamat D. Summer buzz: All you need to know about insect sting allergies.  Pediatrics In review. July 2020; 41(7): 348-356. 
    • Huang, Jenny; Kaur, Bani; Farooqi, Ahmad; Miah, Tayaba; McGrath, Eric; Seth, Divya; Secord, Elizabeth; Poowuttikul, Pavadee. Elevated Glycated Hemoglobin Is Associated with Reduced Antibody Responses to Vaccinations in Children. Pediatr Allergy Immunol Pulmonol. 2020;33(4):193-198. doi:10.1089/ped.2020.1160

  • Veronica Kwiatkowski

    • Kwiatkowski V, A. Navalpakam , P. Poowuttikul. Idiopathic Hypereosinophilic Syndrome Diagnosed in an Infant: A Case Report. https://www.annallergy.org/article/S1081-1206(22)01543-5/fulltext
    • Kwiatkowski V, Narin Thanaputkaiporn, Pavadee Poowuttikul, MD, MD FAAAAI, NFKB2 Mutation in 2 Siblings with DAVID Syndrome and CVID with Variable Presentation. https://www.jacionline.org/article/S0091-6749(21)01946-1/fulltext
    • Kwiatkowski V, Abigail I. Franco, Maria R. Cordisco, Craig A. Mullen. A rapidly-changing skin lesion in an 11-year-old boy https://publications.aap.org/pediatricsinreview/article-abstract/44/2/96/190487/A-Rapidly-Changing-Skin-Lesion-in-an-11-year-old?redirectedFrom=PDF
    • Sean M Frey , Nicolas P N Goldstein, Kwiatkowski V, Ariel Reinish. Clinical outcomes for young children diagnosed with asthma versus  reactive airway disease https://pubmed.ncbi.nlm.nih.gov/34153535/
    • Kwiatkowski V,  J. Lomas. Positive skin testing to mold in patients with allergic reactions to preservative-free juices          https://www.annallergy.org/article/S1081-1206(20)30782-1/abstract
    • Kwiatkowski V,  J. Lomas. Prevalence of previous tonsillectomy in pediatric patients with eosinophilic esophagitis https://www.annallergy.org/article/S1081-1206(20)30721-3/abstract
    • Kwiatkowski V, Franco AI, Cordisco MR, Mullen CA. A Rapidly Changing Skin Lesion in an 11-year-old Boy. Pediatr Rev. 2023;44(2):96-99. doi:10.1542/pir.2020-004671
    • Frey SM, Goldstein NPN, Kwiatkowski V, Reinish A. Clinical Outcomes for Young Children Diagnosed With Asthma Versus Reactive Airway Disease. Acad Pediatr. 2022;22(1):37-46. doi:10.1016/j.acap.2021.06.009

Recent Faculty Abstracts/Presentations (National)

  • Basil Fathalla, MD

    • Fathalla BM. Clinical Manifestations and MEFV mutations in Children with Familial Mediterranean Fever living in Southeast Michigan. Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID). Toronto, 2023.
    • Banisad E, Benchaala I, Lin X, Fathalla BM. Three Generations with Blau Syndrome: Clinical Course and Outcome of the Timely Treated, Partially Treated, and the Untreated. Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID). Toronto, 2023
    • Maggi RB, Jain A, Fathalla BM. Variable Clinical Phenotypes in Siblings with the same DNASE1L3 Pathogenic Genotype: A Case Report of a Rare form of Monogenic Lupus.Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID). Toronto, 2023.
    • Al-Antary E, Arar R, Gallardo M, Persaud Y, Fathalla B, Rajpurkar M, Bhambhani K. Unusual Presentation of TTP in a Newly Diagnosed Patient with SLE in the Setting of COVID 19. ASPHO (The American Society of Pediatric Hematology / Oncology) Conference, 2021

  • Jenny Huang, MD

    • Troy, A, Huang, N, Ajja, C, Pansare, M, Poowuttikul, P, Thomas, R, Huang, J. Risk Factors for Poor Asthma Control in an Urban Pediatric Population During the COVID-19 Pandemic. Journal of Allergy and Clinical Immunology, 2023
    • Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021

  • Aishwarya Navalpakam

    • Thanaputkaiporn,Narin, Mongkonsritragoon, Wimwipa, Navalpakam, Aishwarya, Poowuttikul, Pavadee. The Use of Picture-based Asthma Action Plan to Improve Asthma care in Inner City Children. Pediatric Academic Society, 2023.
    • Yamak O, Kwiatkowski V, Navalpakam A, Poowuttikul P. IL6ST Hyper IgE Syndrome: Three Family Members with Identical Mutations and Variable Presentations. Journal of Allergy and ClinicalImmunology, 2023
    • Kwiatkowski V, Navalpakam A, Poowuttikul P. Idiopathic Hypereosinophilic Syndrome Diagnosed in an Infant: A Case Report. Annals of Allergy, Asthma and Immunology, 2022
    • Yamak O, Navalpakam A, Poowuttikul P. A Unique Presentation of GATA2 Deficiency, Emberger Syndrome. Annals of Allergy, Asthma and Immunology, 2022.
    • Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021
    • Navalpakam A, Saini S, Seth D, Huang J, Poowuttikul P. A Quality Improvement Initiative to Improve Resident- Physician Practices Regarding Flu Vaccine Administration in Individuals with Egg Allergy. Journal of Allergy and Clinical Immunology, 2021

  • Milind Pansare, MD

    • Troy, A, Huang, N, Ajja, C, Pansare, M, Poowuttikul, P, Thomas, R, Huang, J. Risk Factors for Poor Asthma Control in an Urban Pediatric Population During the COVID-19 Pandemic. Journal of Allergy and Clinical Immunology, 2023
    • Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021
    • E Secord, P Poowuttikul, M Pansare, D Seth, S Saini. Pediatric Emergency Visits for Asthma Drop Significantly with COVID19 School Closure. Journal of Allergy and Clinical Immunology, 2021

  • Pavadee Poowuttikul, MD

    • Yamak O, Kwiatkowski V, Navalpakam A, Poowuttikul P. IL6ST Hyper IgE Syndrome: Three Family Members with Identical Mutations and Variable Presentations. Journal of Allergy and ClinicalImmunology, 2023
    • Troy, A, Huang, N, Ajja, C, Pansare, M, Poowuttikul, P, Thomas, R, Huang, J. Risk Factors for Poor Asthma Control in an Urban Pediatric Population During the COVID-19 Pandemic. Journal of Allergy and Clinical Immunology, 2023
    • Kwiatkowski V, Navalpakam A, Poowuttikul P. Idiopathic Hypereosinophilic Syndrome Diagnosed in an Infant: A Case Report. Annals of Allergy, Asthma and Immunology, 2022
    • Yamak O, Navalpakam A, Poowuttikul P. A Unique Presentation of GATA2 Deficiency, Emberger Syndrome. Annals of Allergy, Asthma and Immunology, 2022.
    • Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021
    • Kwiatkowski V, Thanaputkaiporn N, Poowuttikul P. NFKB2 Mutation in 2 Siblings with DAVID syndrome and CVID with Variable Presentations. Journal of Allergy and Clinical Immunology, 2022.
    • Navalpakam A, Saini S, Seth D, Huang J, Poowuttikul P. A Quality Improvement Initiative to Improve Resident- Physician Practices Regarding Flu Vaccine Administration in Individuals with Egg Allergy. Journal of Allergy and Clinical Immunology, 2021
    • Saini S, Navalpakam A, Seth D, Huang J, Poowuttikul P. Quality Improvement Initiative to Improve Resident-Physician Practices Regarding Peanut Introduction in Infancy. Journal of Allergy and Clinical Immunology, 2021
    • E Secord, P Poowuttikul, M Pansare, D Seth, S Saini. Pediatric Emergency Visits for Asthma Drop Significantly with COVID19 School Closure. Journal of Allergy and Clinical Immunology, 2021

  • Divya Seth, MD

    • Seth D, Nyenhuis SM, Pappalardo AA. Factors Affecting Adaptation of the AAAAI Picture-based Asthma Action Plan: a Survey-Based Study, 2022
    • Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021
    • Navalpakam A, Saini S, Seth D, Huang J, Poowuttikul P. A Quality Improvement Initiative to Improve Resident- Physician Practices Regarding Flu Vaccine Administration in Individuals with Egg Allergy. Journal of Allergy and Clinical Immunology, 2021
    • Saini S, Navalpakam A, Seth D, Huang J, Poowuttikul P. Quality Improvement Initiative to Improve Resident-Physician Practices Regarding Peanut Introduction in Infancy. Journal of Allergy and Clinical Immunology, 2021

Recent Faculty Grants

  • Pavadee Poowuttikul, MD

    Role: Grant Director, Percent Effort: 35% 

    Title: "Primary Immunodeficiencies Coordinating Center for Severe Combined Immunodeficiency Newborn Screening Program" Source: Michigan Department of Community Health-SCID NBS 

    Total Period of Support: 1 year 10/2020-09/2021 


    Role: PI, Percent Effort: 10% (no salary support) 

    Title: "Immunosuppression from Systemic Steroid Bursts in Asthma" Source: Children's Hospital of Michigan Foundation R1-2020-78 

    Total Period of Support: 2 year 01/2020-12/2021 


    Role: PI, Percent Effort: 10% (no salary support) 

    Title: "Picture-based Asthma Action Plan" Source: American Academy of Allergy, Asthma and Immunology (AAAAI) 

    Total Period of Support: 3 year 11/2017-11/2020 


Recent Faculty Awards & Other Professional Accomplishments

  • Jenny Huang, MD

    • Awards:
    • Resident Teaching Award. Children's Hospital of Michigan

    Wolf W. Zuelzer Fellow Research Award Finalist Competition – Third place


  • Milind Pansare, MD

    Other Professional Accomplishments:

    • Manuscript reviewer for Annals of Allergy, Asthma and Immunology. Reviewed 5 manuscripts in year 2020. 
    • Abstract reviewer for American Academy of Asthma, Allergy and Immunology (AAAAI).6 abstracts in year 2020. 
    • Group leader for In-Training Examination committee-Wrote and reviewed in-training examination questions(Total-50Q) for fellows-in-training. Oct 2020 to Dec 2020. 
    • Faculty and Mentor in the 2020 Online Workshop (July 13th - August 8th) 
    • In Global Health Research & Fieldwork Practices organized by the Global Health Research Collaborative & the Wayne State University School of Medicine. Lead a group discussion on pediatric anaphylaxis and areas of research Mentor/Advise-latex allergy for researcher from Central America

  • Pavadee Poowuttikul, MD

    Awards:

    • Hour Magazine "Top Doc" 2020

    Other Professional Accomplishments:

    • American Academy of Allergy, Asthma and Immunology (AAAAI) Office of School-based Management of Asthma Taskforce 
    • American Academy of Allergy, Asthma and Immunology (AAAAI) Primary Immunodeficiency Diseases Committee 
    • American Academy of Allergy, Asthma and Immunology (AAAAI) Fellow-In-Training Examination Committee 
    • American Academy of Allergy, Asthma and Immunology (AAAAI) Health Informatics, Technology & Education (HITE) Committee

  • Divya Seth, MD

    Other Professional Accomplishments:

    • Approved for Fellow status in American Academy of Allergy, Asthma and Immunology (AAAAI)-March 2020

  • Aishwarya Navalpakam

    Awards:

    • Journeys & Frontiers in Pediatric Research Program Awardee
    • AAAAI Leadership Institute Mentorship Program Awardee: Leadership project – Survey project regarding climate change curriculum in Allergy/Immunology fellowship
    • Wolf W. Zuelzer Fellow Research Award Recipient, First Place

    Other Professional Accomplishments:

    • Vice Chair of the Bylaw Review Committee for CMUCOM

  • Basil Fathalla, MD

    Awards:

    • Associate Professor Teacher of the Year Award, Children's Hospital of Michigan / DMC Pediatric Residency Program
    • TOP DOCS’ Hour Detroit Magazine

    Other Professional Accomplishments:

    • Founder, Founding member of Pediatric Rheumatology Arab Group-PRAG a subgroup of ARLAR (Arab League Against Rheumatism)

Advocacy & Other Special Areas of Focus

Our faculty are committee members in the American Academy of Allergy, Asthma, and Immunology (AAAAI), American College of Allergy, Asthma and Immunology (ACAAI), American Board of Allergy and Immunology (ABAI)


  • School-based Asthma Management Program (SAMPRO™) committee: faculty serves as chair of the committee
  • AAAAI Leadership Institute
  • Leadership project with AAAAI Website, Internet, and Related Technologies (WIRT) to lead an innovative project on implementing picture-based asthma action plan for AAAAI and School-based Asthma Management Program. 
  • AAAAI Committee on the Underserved with an interest in food insecurity and patients living in inner-city with food allergies. 
  • Women’s Health in Allergy/Immunology: with an interest in creating educational modules for health care providers caring for pregnant people with asthma
  • Fellow-In-Training Examination Committee: 2 of our faculty members were selected to write questions for the Fellow-In-Training Examination questions 
  • Test Writing Committee of the ABAI: one of our faculty members was selected to write questions for the ABAI
  • One of our faculty members was selected to be an ABAI ambassador


Our faculty members are involved in the Central Michigan University College of Medicine (CMUCOM) and Children’s Hospital of Michigan committees including:


  • One of our faculty members is the Vice Chair of the Bylaw Review Committee for CMUCOM
  • One of our faculty members is on Central Michigan University Pediatric Department’s Academic Promotion Committee and the University Pediatricians Advisory Board


The Division participates in the American College of Allergy, Asthma and Immunology Asthma (ACAAI) Screening Camp. 

We also participate in the Immune Deficiency Foundation (IDF) activities, including organizing IDF walk yearly in Detroit, Michigan. IDF is a non-profit organization that seeks to improve diagnosis, treatment, and quality of life for people with primary immune deficiency (PID) by fostering a community empowered by advocacy, education, and research. The IDF achieves their goals as a resource for education materials, publications, conferences, provider referrals, research, public policy advocacy, and through health care provider education. The IDF walk is a community event that supports and connects the PID community and also is a major fundraiser to support the mission of the IDF. Our staff coordinated and held the walk on our campus beginning in 2018. We started as a local walk and are now recognized as a national walk site. Our Immunology nurse serves on the Nurse Advisory Committee of the IDF.


The Division also participates in the IDF/United States Immunodeficiency Network (USIDNET) registry. The USIDNET is a research consortium established to advance scientific research in the field of primary immunodeficiency diseases with current focus on the primary immunodeficiency disease registry, education and mentoring for young investigators. The USIDNET registry is a national patient consented registry for individuals with primary immunodeficiency diseases. The goals are to advance research in the field and to improve the quality of life of patients. It is managed by leading immunologists and administered by the Immune Deficiency Foundation (IDF). Our faculty and nurses have enrolled patients into the USIDNET/FILL registry, have supported registry development, and the Children’s Hospital of Michigan was the first enrolling site in Michigan. Our faculty serves on the Severe Combined Immunodeficiency Disease specific work group of the USIDNET – IDF.


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