Infectious Diseases

University Pediatricians | Michigan

About the Division of Infectious Diseases

Specialists in the Division of Infectious Diseases at the Children's Hospital of Michigan (CHM) provide a wide range of consultative and direct care services for all types of infectious diseases in patients ranging from birth to 21 years of age. These services include diagnosis and management of difficult infectious diseases cases as well as antibiotic recommendations.


 A 26-bed inpatient unit is devoted for the care of patients with infectious diseases under the direct supervision of one of the attending staff. Nurses on the unit are dedicated to the care of such patients. The division also provides consultative service to all other medical and surgical units at CHM.


Outpatient referrals and consultations can be seen during three days of the week (Mondays, Wednesdays, and Fridays) in the afternoon with prior appointment. Acute and urgent cases may be referred to the Emergency Department at CHM, where Infectious Diseases staff may be consulted to see the patients.


Research interests are wide but focus mainly on bacterial and viral infections. Main areas of interest are the treatment of various infections with newer antimicrobial agents, assessment of new vaccines, and the study of otitis media, respiratory infections, Kawasaki Disease, endocarditis, and rheumatic fever.

Leadership

Division Chief: Basim I. Asmar, MD

Faculty

Faculty


Advanced Practice Providers

  • Jillian White, CNP

Want to learn more about our distinguished specialists? Click the button below to be taken to our Faculty Directory.

Faculty Directory →

Education

The Pediatric Infectious Diseases Fellowship at the Children's Hospital of Michigan is an ACGME approved program. The major goal of the program is to train infectious diseases fellows in a progressive manner to become highly competent subspecialists.

Click here or on the button below to learn more about the Pediatric Infectious Diseases Fellowship.

Infectious Diseases Fellowships →

Research

Recent Faculty Publications

  • Basim Asmar, MD

    • Abdel-Haq N, Asmar BI, Deza Leon MP, McGrath EJ, Arora HS, Cashen K, Tilford B, Charaf Eddine A, Sethuraman U, Ang JY. SARS-CoV-2-Associated Multisystem Inflammatory Syndrome in Children: Clinical Manifestations and the Role of Infliximab Treatment. European Journal of Pediatrics. In press. 
    • Arora HS, Kamat D, Choudhry S, Asmar BI, Abdel-Haq N. Are Stethoscopes, Coats, and Pagers Potential Sources of Healthcare Associated Infections?. Glob Pediatr Health. 2020 Oct 29;7:2333794X20969285. doi: 10.1177/2333794X20969285. 
    • Kim E, Asmar BI, Thomas R, Abdel-Haq N. Cytomegalovirus viremia and resistance patterns in immunocompromised children: An 11-year experience. Pediatr Hematol Oncol. 2020 Mar;37(2):119-128. doi: 10.1080/08880018.2019.1695031. 
    • Deza Leon MP, Redzepi A, McGrath E, Abdel-Haq N, Shawaqfeh A, Sethuraman U, Tilford B, Chopra T, Arora H, Ang J, Asmar B. COVID-19-Associated Pediatric Multisystem Inflammatory Syndrome. J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):407-408. doi: 10.1093. 

  • Nahed Abdel-Haq, MD

    • Abdel-Haq N, Asmar BI, Deza Leon MP, McGrath EJ, Arora HS, Cashen K, Tilford B, Charaf Eddine A, Sethuraman U, Ang JY. SARS-CoV-2-Associated Multisystem Inflammatory Syndrome in Children: Clinical Manifestations and the Role of Infliximab Treatment. European Journal of Pediatrics. In press. 
    • Rafee Y, Abdel-Haq N. A Child with Kawasaki Disease and Coronary Artery Aneurysm During Acute Epstein-Barr Virus Infection: A Closer Look at Immunopathogenesis. Infect Dis Clin Pract 2020. November 6, 2020 – Volume- Publish Ahead of Print - Issue -doi: 10.1097/IPC.0000000000000956. 
    • Arora HS, Kamat D, Choudhry S, Asmar BI, Abdel-Haq N. Are Stethoscopes, Coats, and Pagers Potential Sources of Healthcare Associated Infections?. Glob Pediatr Health. 2020 Oct 29;7:2333794X20969285. doi: 10.1177/2333794X20969285. 
    • Kim E, Asmar BI, Thomas R, Abdel-Haq N. Cytomegalovirus viremia and resistance patterns in immunocompromised children: An 11-year experience. Pediatr Hematol Oncol. 2020 Mar;37(2):119-128. doi: 10.1080/08880018.2019.1695031. 
    • Molloy L, Barron S, Khan N, Abrass E, Ang J, Abdel-Haq N. Oral beta-lactam antibiotics for pediatric otitis media, rhinosinusitis and pneumonia. J Pediatr Health Care. 2020 May-Jun;34(3):291-300. doi: 10.1016/j.pedhc.2019.11.001.. 
    • Deza Leon MP, Redzepi A, McGrath E, Abdel-Haq N, Shawaqfeh A, Sethuraman U, Tilford B, Chopra T, Arora H, Ang J, Asmar B. COVID-19-Associated Pediatric Multisystem Inflammatory Syndrome. J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):407-408. doi: 10.1093. 

  • Harbir Arora, MD

    • Arora HS, Kamat D, Choudhry S, Asmar BI, Abdel-Haq N. Are Stethoscopes, Coats, and Pagers Potential Sources of Healthcare Associated Infections? Global Pediatric Health. 2020 Oct 29; Volume 7, 1-7. 
    • Harbir Arora MD. A to Z of Zika Virus. A comprehensive review for clinicians. Global Pediatric Health, Volume 7, 1-14, 2020. PMID: 32529004 
    • Deza COVID-19 Associated Pediatric Multi-System Inflammatory Syndrome. Deza Leon MP, Redzepi A, McGrath E, Abdel-Haq N, Shawaqfeh A, Sethuraman U, Tilford B, Chopra T, Arora H, Ang J, Asmar B. J Pediatric Infect Dis Soc. 2020 May 22 2020. PMID: 32441749 

  • Jocelyn Ang, MD

    • Abdel-Haq N, Basim A, Deza Leon M, McGrath E, Arora H, Cashen K, Tilford B, Charaf Eddine A, Sethuraman U, Ang JY. SARS-CoV-2-Associated Multisystem Inflammatory Syndrome in Children: Clinical Manifestations and the Role of Infliximab Treatment. European J of Pediatrics. In Press 
    • Pitman-Hunt C, Leja J, Jiwani ZM, Rondot D, Ang J, Kannikeswaran N. SARS-CoV-2 Transmission in an Urban Community: The Role of Children and Household Contacts. J Pediatric Infect Dis Soc. 2020 Nov 27:piaa158. doi: 10.1093/jpids/piaa158. Epub ahead of print. PMID: 33245123; PMCID: PMC7717291. 
    • Sethuraman U, Kannikeswaran N, Ang J, Singer A, Miller J, Haddad R, Stankovic C. Multisystem inflammatory syndrome in children associated with novel coronavirus SARS-CoV-2: Presentations to a pediatric emergency department in Michigan. Am J Emerg Med. 2020 Oct 24:S0735-6757(20)30931-1. doi: 10.1016/j.ajem.2020.10.035. Epub ahead of print. PMID: 33131972. 
    • Dove ML, Jaggi P, Kelleman M, Abuali M, Ang JY, Ballan W, Basu SK, Campbell MJ, Chikkabyrappa SM, Choueiter NF, Clouser KN, Corwin D, Edwards A, Gertz SJ, Ghassemzadeh R, Jarrah RJ, Katz SE, Knutson SM, Kuebler JD, Lighter J, Mikesell C, Mongkolrattanothai K, Morton T, Nakra NA, Olivero R, Osborne CM, Panesar LE, Parsons S, Patel RM, Schuette J, Thacker D, Tremoulet AH, Vidwan NK, Oster ME. Multisystem Inflammatory Syndrome in Children: Survey of Protocols for Early Hospital Evaluation and Management. J Pediatr. 2020 Oct 16:S0022-3476(20)31293-2. Doi 10.1016/j.jpeds.2020.10.026. Epub ahead of print. PMID: 33075369; PMCID: PMC7566788. 
    • Arrieta AC, Ang JY, Zhang Z, et al. Plasma pharmacokinetics of ceftolozane/tazobactam in pediatric patients with cystic fibrosis. Pediatr Pulmonol. 2020;55(8):2025-2032. Epub 2020 May 18. doi:10.1002/ppul.24815 PMID: 32421928 
    • Molloy L, Abdulhamid I, Srivastava R, Ang JY. Ceftolozane/Tazobactam Treatment of Multidrug-resistant Pseudomonas aeruginosa Infections in Children. Pediatr Infect Dis J. 2020;39(5):419-420. 2020 May;39(5):419-420. doi:10.1097/INF.0000000000002593 PMID: 32032173 
    • Ang JY, Arrieta A, Bradley JS, et al. Ceftolozane/Tazobactam in Neonates and Young Infants: The Challenges of Collecting Pharmacokinetics and Safety Data in This Vulnerable Patient Population [published online ahead of print, 2020 Jan 7]. Am J Perinatol. 2020;10.1055/s-0039-3402719. doi:10.1055/s-0039-3402719. PMID: 31910460 
    • Molloy L, Barron S, Khan N, Abrass E, Ang J, Abdel-Haq N. Oral β-Lactam Antibiotics for Pediatric Otitis Media, Rhinosinusitis, and Pneumonia. J Pediatr Health Care. 2020;34(3):291-300. doi:10.1016/j.pedhc.2019.11.001 PMID: 32334748 
    • McGrath E, Jadcherla Y*, Held J*, Ang JY. A Real Pain in the Neck. Clin Pediatr (Phila). 2020 Oct 30:9922820970173. doi: 10.1177/0009922820970173. Epub ahead of print. PMID: 33124445. 
    • D Doctor P*, Ang J, Asmar B, McGrath E. Spinal Abscess in a Patient with Undiagnosed Congenital Dermal Sinus Tract. Glob Pediatr Health. 2020 Sep 25;7:2333794X20953324. doi: 10.1177/2333794X20953324. PMID: 33029551; PMCID: PMC7522820. 
    • Henry M*, Horton L*, Ang JY. Unexplained Direct Hyperbilirubinemia and New-Onset Shock in a 17-Year-Old Male. Glob Pediatr Health. 2020;7:2333794X20919596. Published 2020 May 29. doi:10.1177/2333794X20919596 PMID: 32529005 
    • Chang TF*, Ang JY. A Case of a Mediastinal Mass in a Teenager Causing Chest Pain, Difficulty Breathing, and Emesis: A Rare Complication of a Relatively Common Disease. Clin Pediatr (Phila). 2020;59(8):837-840. Epub 2020 Apr 26. doi:10.1177/0009922820915888 PMID: 31267761 
    • Dabaja E*, Daoud R*, Alquadan O*, Ang JY. A Case of a Rare Tick-Borne Illness in Michigan Associated With Reversible Splenial Lesion Syndrome: When It Is Not a Viral Exanthem. Clin Pediatr (Phila). 2020;59(9-10):938-942. Epub 2020 Apr 4.doi:10.1177/0009922820913962 PMID: 32248700 - (Publications with learners*) 
    • Deza Leon MP, Redzepi A, McGrath E, Abdel-Haq N, Shawaqfeh A, Sethuraman U, Tilford B, Chopra T, Arora H, Ang J, Asmar Bl. COVID-19-Associated Pediatric Multisystem Inflammatory Syndrome. J Pediatric Infect Dis Soc. 2020;9(3):407-408. doi:10.1093/jpids/piaa061 PMID: 32441749 

Recent Faculty Abstracts/Presentations (National)

  • Nahed Abdel-Haq, MD

    • Firmani SE, Molloy L, Trivedi G, Abdel-Haq N. Institutional Antibiograms Are Insufficient to Guide Clindamycin Use in Pediatric Skin and Soft Tissue Infections. ID Week, October 21-25, 2020. 1349. Open Forum Infectious Diseases, Volume 7, Issue Supplement_1, October 2020, Page S685, https://doi.org/10.1093/ofid/ofaa439.1531

  • Jocelyn Ang, MD

    • Ang JY, Nirupama Kannikeswaran N, Parker K, Asmar B . Clinical Presenting Characteristics of Pediatric COVID-19 Infection in a Tertiary Care Children’s Hospital in Detroit. ID Week 2020, October 21-25, 2020.

  • Basim Asmar, MD

    • Ang JY, Nirupama Kannikeswaran N, Parker K, Asmar B . Clinical Presenting Characteristics of Pediatric COVID-19 Infection in a Tertiary Care Children’s Hospital in Detroit. IDWeek 2020, October 21-25, 2020. (Infectious Diseases Society of America annual meeting). 

Recent Faculty Grants

  • Jocelyn Ang, MD

    Site Principal Investigator 

    Title: (CHARMS) Characterization of Multisystem Inflammatory Syndrome in Children and its relationship to Kawasaki disease (KD) Source: Patient-Centered Outcomes Research Institute 2020- Total Direct Costs: $12,600 per year 


    Site Principal Investigator 

    Title: A Phase 1, Non-comparative, Open-Label Study of Pharmacokinetics and Safety of a Single-Dose of ZTI-01 (Fosfomycin for Injection) in Pediatric Subjects (Less than 12 years of Age) Receiving Standard of Care Antibiotic Therapy for Proven or Suspected Infection or for Peri-operative Prophylaxis 

    Source: Zavante Pharmaceuticals Inc. 2018- present Total Direct Costs: $83,180.2 


    Site Principal Investigator 

    Title: A phase III randomized, active-comparator-controlled clinical trial to study the safety and efficacy of MK-1986 (tedizolid phosphate TDZ) and comparator, in subjects 3 months to <12 years of age with Acute Bacterial Skin and Skin Structure Infections (ABSSSI) 

    Source: Merck Pharmaceuticals Inc. 2018-2000 Total Direct Costs: $245,395.80

Recent Faculty Awards & Other Professional Accomplishments

  • Nahed Abdel-Haq, DO

    Awards: 

    • Hour Magazine "Top Doc" 2020

  • Jocelyn Ang, MD

    Other Professional Accomplishments:

    • Invited speaker, “Multisystem Inflammatory Disease in Children associated with COVID-19 in Detroit”, the International Cyber Symposium on COVID19 and Kawasaki Disease at the 40 Scientific Meeting of Japanese Society of Kawasaki Disease. October 30-31, 2020. 
    • Invited Speaker, “Epidemiology, Presentation, Diagnosis and Management of COVID-19 in Children”, the 2020 VIRTUAL Annual Fall Scientific Conference of the Michigan Infectious Disease Society and Michigan Department of Health and Human Services. Thursday, November 12, 2020. 
    • Speaker, Virtual Symposium: “COVID – How Are We Doing?” Wayne State University Saturday, September 12th, 2020. 
    • Speaker, ID grand rounds, MIS-C CHM, Detroit, Michigan, May 2020. 
    • Speaker, 11th Pediatric Annual Board Review, CHM, Detroit, Michigan, April 10, 2020 - Research presentation and panelist. The impacts of COVID-19 on children and families. Virtual symposium Central Michigan University College of Medicine. November 9, 2020.
    • Participant on the Topic of COVID-19. Central Michigan University. Shifting Mindsets for Better Health podcast. September 25, 2020. 
    • Developed Protocol for Treatment of COVID-19 infection at Children’s Hospital of Michigan - Developed Protocol for treatment of MIS-C at Children’s hospital of Michigan

  • Basim Asmar, MD

    Awards:

    • Wayne State School of Medicine 2019-2020 Faculty Teaching Award 
    • Hour Detroit Magazine TOP DOC 2020 
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