Neurology
University Pediatricians | Michigan
About the Division of Neurology
The Division of Pediatric Neurology at Children’s Hospital of Michigan is dedicated to providing comprehensive, evidence-based, and compassionate care for infants, children, and adolescents with neurological disorders.
Our team of board-certified child neurologists and advanced practice providers delivers high-quality, patient-centered care across the full spectrum of pediatric neurological conditions. We work in close collaboration with pediatric neurosurgeons, neuroradiologists, intensivists, neonatologists, rehabilitation specialists, and primary care providers to ensure coordinated and individualized treatment—particularly in complex clinical situations. We are supported by state-of-the-art diagnostic and imaging resources, including:
Our Electroneurodiagnostic (EEG) Laboratory is accredited by the American Board of Registration of Electroencephalographic and Evoked Potential Technologists (ABRET), reflecting excellence in EEG acquisition and neurophysiological testing.
From the Chief
Welcome to the Division of Pediatric Neurology. Our mission is to provide the highest level of care for children with neurological conditions while advancing knowledge through education and research. Our team of dedicated clinicians, educators, and researchers works collaboratively to deliver accurate diagnoses, thoughtful treatments, and compassionate, family-centered care.
We emphasize a multidisciplinary, coordinated approach that integrates expertise across specialties and partners closely with families at every stage. Supported by advanced neuroimaging and neurophysiological tools, we provide precise, individualized care to improve outcomes for children locally, nationally, and internationally, while training the next generation of leaders in pediatric neurology. We look forward to partnering in your child’s care.
Aimee L. Luat, MD
Chief, Division of Pediatric Neurology
Leading the Way in Pediatric Epilepsy Care
Discover how expert care, cutting-edge treatment, and family-centered support come together to change lives in this inspiring look at the Pediatric Epilepsy Program.
National Recognition and Specialized Care
The Pediatric Neurology and Neurosurgery programs at Children’s Hospital of Michigan have been ranked among the nation’s Best Children’s Hospitals by U.S. News & World Report for over a decade.
Our division offers expertise in:
We are proud to be part of a Level 4 Epilepsy Center, designated by the National Association of Epilepsy Centers—the highest level of recognition—indicating advanced capability in the medical and surgical management of complex epilepsy, including intracranial EEG monitoring, resective epilepsy surgery, and neuromodulation. Our physicians are actively engaged in academic medicine, contribute extensively to peer-reviewed journals, and hold subspecialty certifications across pediatric neurology disciplines.
Academic Excellence and Training
All faculty members hold academic appointments at Central Michigan University College of Medicine and are deeply committed to education and research.
Training Programs:
– ACGME-accredited Child Neurology Residency (3 residents per year)
– ACGME-accredited Pediatric Epilepsy Fellowship, offered in collaboration with adult neurology at the Detroit Medical Center
We train medical students, residents, fellows, and visiting physicians from around the world, fostering the next generation of clinician-scientists.
Research and Innovation
Our division maintains a strong commitment to advancing the field of pediatric neurology through research and innovation.
– Over 200 peer-reviewed publications in the past decade
– Continuous support from competitive federal research funding
– Focus on improving diagnostic accuracy and therapeutic outcomes
– Leadership in epilepsy, neurophysiology, neuroimaging, neuropsychology, and neuromuscular research
We actively translate scientific discoveries into clinical practice to improve care for children with neurological disorders.
Our Clinical Programs Include
Our pediatric neurologists work closely with our experienced pediatric neurology nurse practitioners to provide comprehensive evaluation and management for children with a wide range of neurological conditions, including headaches, dizziness, seizures, muscle weakness, and various neurodevelopmental disorders. This collaborative partnership plays a critical role in expanding patient access to high-quality neurological care.
The Brachial Plexus Clinic provides specialized, multidisciplinary care for children with brachial plexus injuries and related peripheral nerve disorders. Our team includes experts in pediatric neurology, neurosurgery, orthopedic surgery, and rehabilitation therapies, working together to evaluate nerve function and guide treatment. We offer comprehensive assessment, including clinical evaluation and electrodiagnostic studies, to support accurate diagnosis and prognosis. Treatment plans are individualized and may include physical and occupational therapy, neuromuscular rehabilitation, and, when appropriate, surgical intervention, with the goal of maximizing functional recovery and long-term outcomes.
Our Concussion Clinic provides multidisciplinary care led by a pediatric neurologist, neuropsychologist, and nurse coordinator. Children are evaluated soon after a concussion, and we develop individualized recovery plans that emphasize a safe and timely return to school, sports, and normal daily activities.
Children with new-onset seizures are evaluated promptly by board certified pediatric neurologists and pediatric epilepsy specialists with extensive expertise in seizure diagnosis and management. Comprehensive neurodiagnostic services, including EEG and overnight Epilepsy Monitoring Unit studies, are available at our Detroit and Troy locations. For children who may benefit from dietary therapy, including the ketogenic diet, care is supported by a dedicated dietitian with specialized expertise.
For patients whose seizures are not adequately controlled with medication alone (drug resistant epilepsy), we offer additional treatment options such as neuromodulation (vagus nerve stimulation: VNS; responsive neurostimulation: RNS; deep brain stimulation: DBS) and highly specialized resective epilepsy surgery. In partnership with our pediatric neurosurgery colleagues, Children’s Hospital of Michigan performs approximately 25 epilepsy surgeries annually. We also offer advanced genetic diagnostic services, which are increasingly relevant in the evaluation and treatment planning of children with complex seizure disorders.
The Functional Neurological Disorders (FND) Clinic provides a multidisciplinary specialized care for children with neurological symptoms not explained by structural disease, including functional seizures (psychogenic non-epileptic events), movement disorders, and conversion disorders. Our multidisciplinary team includes pediatric neurology, psychology/neuropsychology, and rehabilitation specialists who work together to establish an accurate diagnosis and develop individualized treatment plans. Care focuses on education, symptom management, and evidence-based therapies aimed at restoring function and improving quality of life in a supportive, family-centered environment.
The Multiple Sclerosis Clinic provides specialized care for children and adolescents with multiple sclerosis and related demyelinating disorders. We offer comprehensive diagnostic evaluation, including advanced neuroimaging and laboratory testing, to characterize disease and guide management. Treatment plans are individualized and may include disease-modifying therapies and immunotherapies aimed at reducing relapse risk and preserving neurological function. Through coordinated, multidisciplinary care, we support patients and families in symptom management, longitudinal monitoring, and maintenance of quality of life.
The Muscular Dystrophy Clinic, designated as a Muscular Dystrophy Association (MDA) Care Center, provides comprehensive, multidisciplinary care for children with suspected or confirmed neuromuscular disorders. Our team includes specialists in neuromuscular disorder, genetics, pediatric physical medicine and rehabilitation, occupational and physical therapy, nutrition, and neuropsychology, working collaboratively to support each child’s medical and functional needs.
We offer advanced diagnostic evaluation, including genetic testing, and provide access to the latest treatment options including gene therapy. Our physicians have experience in administering gene therapy and other emerging disease-modifying treatments for eligible patients. Through coordinated, team-based care, we aim to optimize mobility, function, and quality of life for children and their families.
The Neurofibromatosis (NF) Clinic provides specialized, multidisciplinary care for children with neurofibromatosis and related tumor predisposition syndromes, including NF1, NF2, and schwannomatosis. Our team includes experts in pediatric neurology, neuropsychology, oncology, genetics, physical medicine and rehabilitation, ophthalmology, and other subspecialties, working collaboratively to monitor and manage the diverse manifestations of these conditions. We offer comprehensive evaluation, including advanced imaging and genetic testing, to guide diagnosis and longitudinal care. Treatment plans are individualized and may include surveillance, medical therapy, and coordination of surgical care when needed, with a focus on optimizing neurological function, growth, and quality of life.
The Neurogenetics Clinic provides specialized care for children with suspected or confirmed genetic disorders affecting the nervous system. Our team offers comprehensive evaluation, including detailed clinical assessment and advanced genetic testing, to establish an accurate diagnosis. We manage a wide range of conditions, including developmental and epileptic encephalopathies, neurometabolic disorders, neurodevelopmental syndromes, and inherited neuromuscular diseases. Care is individualized and may include targeted therapies, coordination with subspecialists, and genetic counseling for families. Our goal is to guide diagnosis, inform treatment decisions, and support long-term neurological health.
The Neuroimmunology Clinic provides specialized care for children with immune-mediated disorders of the nervous system. Our team has expertise in the diagnosis and management of autoimmune neurological conditions, including autoimmune encephalitis and related inflammatory diseases. We offer comprehensive evaluation using advanced neuroimaging, laboratory testing, and antibody studies to support accurate diagnosis. Treatment strategies include individualized immunotherapy aimed at reducing disease activity, preventing relapse, and optimizing long-term neurological outcomes through coordinated, multidisciplinary care.
Our Division includes a dedicated Neurohospitalist service, ensuring continuous, expert neurological care for hospitalized children. A pediatric neurohospitalist is available to provide timely consultation, inpatient management, and coordination of care for a wide range of acute neurological conditions. This model enhances communication among care teams, supports efficient decision-making, and ensures seamless transitions between inpatient and outpatient care.
Our Sleep Disorders Clinic provides comprehensive care for children with sleep-related conditions. Supported by a dedicated sleep laboratory, we evaluate and treat disorders such as obstructive sleep apnea, behavioral insomnia, and narcolepsy. Overnight sleep studies are available at our Specialty Center–Detroit and Children’s Hospital of Michigan–Troy locations.
The Sturge–Weber Syndrome Clinic provides specialized, multidisciplinary care for children with this rare neurocutaneous disorder, which affects the brain, skin, and eyes. Our team has expertise in the diagnosis and management of neurological complications, including seizures, stroke-like episodes, developmental challenges, and associated ophthalmologic conditions such as glaucoma. We have a long-time collaboration with the Sturge-Weber Foundation (SWF) and our center is among the >25 SWF Clinical Care Network centers known nationally and internationally. We offer comprehensive evaluation using advanced neuroimaging and neurophysiological testing to guide individualized treatment planning. Care is coordinated across specialties to optimize neurological outcomes and support long-term health and quality of life.
Our Tuberous Sclerosis Complex (TSC) Clinic is one of the TS Alliance recognized clinic providing comprehensive, multidisciplinary care for children with TSC, a genetic condition that can affect the brain, skin, kidneys, heart, and other organs. Our team includes specialists in pediatric neurology, neurosurgery, nephrology, cardiology, dermatology, genetics, ophthalmology and other disciplines, working together to address the complex needs of each patient. We offer advanced diagnostic evaluation, including neuroimaging and genetic testing, and provide individualized treatment plans for epilepsy, developmental concerns, and systemic manifestations of TSC. Our goal is to optimize neurological and overall health outcomes through coordinated, long-term care.
Appointments
Child Neurology services are provided at multiple Children’s Hospital of Michigan Specialty Center locations that are convenient to your patients including:
Specialty Center – Canton
45250 Cherry Hill Road, Canton, MI 48187
Stilson Specialty Center – Clinton Township
42700 Garfield Road, Clinton Township, MI 48038
Specialty Center – Dearborn
25325 Ford Road, Dearborn, MI 48128
Specialty Center Detroit
3950 Beaubien Street, Detroit, MI 48201
Alex J. Etkin Specialty Center – Southfield
29120 Franklin Road, Southfield, MI 48034
Children’s Hospital of Michigan – Troy
350 W. Big Beaver Road, Troy, MI 48084
To schedule an appointment with a Pediatric Neurologist, please call (313) 832-9620 and select Option 1.
For a second opinion regarding seizures or epilepsy, please call (313) 832-9610.
To schedule an EEG or long-term video-EEG monitoring appointment, please call (313) 745-5562 and select Option 1.
All MRI studies, with or without sedation, are available at our Detroit and Troy locations. All imaging studies are interpreted by fellowship-trained, board-certified pediatric neuroradiologists.
Our Team is Dedicated to You
Pediatric Neurology Attendings
Learn about our University Pediatricians Attendings
Assistant Professor of Pediatrics and Neurology at Central Michigan University
Assistant Professor of Pediatrics and Neurology at Central Michigan University
Advanced Practice Providers
Want to learn more about our distinguished specialists? Click the button below to be taken to our Faculty Directory.
Recent Research Publications
Norimitsu Kuwabara, MD
Pediatric Epilepsy; In Textbook of Symptom-Based Approach to Pediatric Neurology. Kuwabara N, James Wheless. Springer Nature, to be published in October 2021.
Aimee Luat, MD
Mitsuhashi T, Sonoda M, Iwaki H, Luat AF, Sood S, Asano E. Effects of depth electrode montage and single-pulse electric stimulation sites on neuronal responses and effective connectivity. Clin Neurophysiol 2020; 131:2781-2792.
Felippe B, Abushama A, Morrison-Levy N, Puneet J, Vinayan KP, Abudkhalid, M, Aldhalaan H, Almuzaini H, Sheffali G, Hershkovitz T, Konanki R, Lingappa L, Luat AF, Shafi S, Tabarki B, Thomas M, Yoganathan S, Alfadhel M, Arya R, Donner E, Ehaideb S, Gowda V, Jain V, Madaan P, Myers K, Otsubo H, Panda P, Sahu JK, Sampaio L, Sharma S, Tremblay E, Zak M, Whitney R. KCNT1-related epilepsy: An international multicenter cohort of 27 pediatric cases. Epilepsia 2020; March 13. Doi: 10.1111/epi.16480.
Sood, S, Asano E, Luat AF. Minimizing blood loss in hemispherectomy for hemimegalencephaly in low-weight infants: technical note. Child’s Nervous System 2020 April; 36 (4): 841-845. doi: 10.1007/s00381-020-04534-5.
Naznin Mahmood, MD
Co-Authored “Chronic Headaches in Children” chapter with Lalitha Sivaswamy MD in the book “Symptom Based Approach to Pediatric Neurology”—coeditors Dr. Lalitha Sivaswamy & Dr. Deepak Kamat.
Lalitha Sivaswamy, MD
Diagnosing Pseudotumor Cerebri: An Age-based Approach. Tuhina Govil-Dalela, Lalitha Sivaswamy. Pediatr Neurol Briefs. 2020; 34: 19. Published online 2020 Dec 18. doi: 10.15844/pedneurbriefs-34-19 PMCID: PMC7747552 ArticlePubReaderPDF–139KCitation Select item 7718100
Quality of Life in Multiple Sclerosis Mitchell T. Williams, Lalitha Sivaswamy. Pediatr Neurol Briefs. 2020; 34: 14. Published online 2020 Dec 4. doi: 10.15844/pedneurbriefs-34-14 PMCID: PMC7718100 ArticlePubReaderPDF–138KCitation
A Teenager With Facial Numbness. Mandle Q, Kannikeswaran S, Surapaneni M, Sivaswamy L. Pediatr Neurol. 2020 Mar;104:68-69. doi: 10.1016/j.pediatrneurol.2019.07.002. Epub 2019 Jul 17.PMID: 31409503 No abstract available.
Rapid Sequence MRI Protocol in the Evaluation of Pediatric Brain Attacks. De Jong G, Kannikeswaran N, DeLaroche A, Farooqi A, Sivaswamy L. Pediatr Neurol. 2020 Jun;107:77-83. doi: 10.1016/j.pediatrneurol.2019.12.007. Epub 2019 Dec 27. PMID: 32111563
Daniela Tapos, MD
Paroxysmal dyskinesias and developmental delay: How a detailed history and fasting EEG revealed the diagnosis.” by Imtiaz, Hassan; Weber, Amanda; Can, Afra; Tapos, Daniela
McGregor A, Kuwabara N, Sukhdeo Singh RD, Patel C.
Neurology Board Review: Questions and Answers. Oxford University Press. 2025.
https://doi.org/10.1093/med/9780199895625.001.0001
Luat AF, Hetrick KA.
Pharmaceutical-Grade Cannabidiol in Pediatric Epilepsy. In: Cannabis and the Developing Brain. 2025. Springer.
http://doi.org/10.1007/978-3-031-87990-6_10
Kuwabara N, Wheless JW.
Child with Epilepsy. In: Symptom-Based Approach to Pediatric Neurology. 2023. Springer.
http://doi.org/10.1007/978-3-031-10494-7_10
Luat AF, Chugani HT.
Tuberous Sclerosis Complex. In: Handbook of Pediatric Epilepsy Case Studies, Second Edition. 2023. taylorfrancis.com.
http://doi.org/10.1201/9781003296478-30
Weber A, Luat AF.
Child with New Onset Convulsive Seizure. In: Symptom-Based Approach to Pediatric Neurology. 2023. Springer.
http://doi.org/10.1007/978-3-031-10494-7_7
Mahmood N, Sivaswamy L.
Child with Chronic Headache. In: Symptom-Based Approach to Pediatric Neurology. 2023. Springer.
http://doi.org/10.1007/978-3-031-10494-7_19
Serajee FJ, Huq AHM.
Advances in Tourette Syndrome: Diagnosis and Treatment. In: New Advances in Pediatric Neurologic and Developmental Disorders in the Era of Genomics. Pediatric Clinics of North America. 2023. Elsevier.
http://doi.org/10.1016/j.pcl.2015.03.007
Eishi Asano, MD
Banerjee S, Dong M, Lee MH, O’Hara N*, Juhasz C, Asano E, Jeong JW. Deep relational reasoning for the prediction of language impairment and postoperative seizure outcome using preoperative DWI connectome data of children with focal epilepsy. IEEE Trans Med Imaging 2020. doi: 10.1109/TMI.2020.3036933. (Role: data acquisition; data analysis; critical revision of the manuscript).
Manwar R, Li X, Mahmoodkalayeh S, Asano E, Zhu D, Avanaki K. Deep learning protocol for improved photoacoustic brain imaging. J Biophotonics 2020. doi: 10.1002/jbio.202000212. (Role: Providing the clinical expertise and critical revision of the manuscript).
Mitsuhashi T*, Sonoda M*, Iwaki H*, Luat AF, Sood S, Asano E. Effects of montage and stimulus sites on neuronal responses to single-pulse electrical stimulation on depth electrode recording. Clin Neurophysiol 2020;131:2781-2792. (Featured as the cover figure; Role: Corresponding author).
Yin Q*, Johnson EL*, Tang L*, Auguste KI, Knight RT, Asano E, Ofen N. Direct brain recordings reveal occipital cortex involvement in memory development. Neuropsychologia 2020;148:107625. doi: 10.1016/j.neuropsychologia.2020.107625. (Role: study concept and design; data acquisition; data analysis; critical revision of the manuscript)
Nariai H*, Hussain SA, Bernardo D, Motoi H*, Sonoda M*, Kuroda N*, Asano E, Nguyen JC, Elashoff D, Sankar R, Bragin A, Staba RJ, Wu JY. Scalp EEG interictal high frequency oscillations as an objective EEG biomarker of infantile spasms. Clin Neurophysiol 2020;131:2527-2536. (Role: data analysis; critical revision of the manuscript).
Sugiura A*, Alqatan Z*, Nakai Y*, Kambara T*, Silverstein BH*, Asano E. Neural dynamics during the vocalization of ‘uh’ or ‘um’. Sci Rep 2020;10:11987. doi: 10.1038/s41598-020-68606-x (Role: Corresponding author).
Banerjee S, Dong M, Lee MH, O’Hara N*, Asano E, Jeong JW. Prediction of language impairment using deep relational reasoning. Proc IEEE Int Symp Biomed Imaging 2020. doi: 10.1109/ISBI45749.2020.9098712. (Role: data acquisition; data analysis; critical revision of the manuscript).
Silverstein BH*, Asano E. Dynamic tractography: integrating cortico-cortical evoked potentials and diffusion imaging. Neuroimage 2020;215:116763. doi: 10.1016/j.neuroimage.2020.116763. (Featured as the cover figure; Role: study concept and design; data acquisition; data analysis; critical revision of the manuscript)
Sugiura A*, Sonoda M*, Lee MH, Jeong JW, Lee MH, O’Hara N*, Sonoda M*, Kuroda N*, Juhasz C, Asano E, Dong M, Jeong JW. Novel deep learning network analysis of electrical stimulation mapping-driven diffusion MRI tractography to improve preoperative evaluation of pediatric epilepsy. IEEE Trans Med Imaging 2020;67:3151-3162. (Role: data acquisition; data analysis; critical revision of the manuscript).
Sood S, Asano E, Luat A. Minimizing blood loss in hemispherectomy for hemimegalencephaly in low weight infants – technical note. Child Nerv Syst 2020;36:841-845. (Role: data acquisition; data analysis; critical revision of the manuscript)
Sugiura A*, Silverstein BH*, Jeong JW, Nakai Y*, Sonoda M*, Motoi H*, Asano E. Four-dimensional map of direct effective connectivity from posterior visual areas. Neuroimage 2020;210:116548. doi: 10.1016/j.neuroimage.2020.116548. (Role: Corresponding author).
Asano E.
Dynamic tractography-based assessment of neural interactions along white matter pathways. Invited lecture and workshop chair, Investigator Workshop, 79th Annual Meeting of the American Epilepsy Society (AES), Atlanta, GA, 2025.
How can tractography help us understand the propagation of epileptic activity? Invited lecture, International Conference for Technology and Analysis of Seizures (ICTALS), Université de Montréal, Montreal, QC, Canada, 2025.
How to analyze EEG with advanced methods. Invited lecture, 33rd International Congress of Clinical Neurophysiology, Jakarta, Indonesia, 2024.
Advanced functional mapping in SEEG. Invited lecture, American Clinical Neurophysiology Society (ACNS) Annual Meeting, Austin, TX, 2023.
Luat AF.
Neonatal seizures: Evaluation and management. Invited lecture, Trinity Health Ann Arbor Hospital NICU Conference, Ann Arbor, MI, 2025.
Sturge-Weber syndrome and quality of life. Invited lecture, Sturge-Weber Foundation Clinical Care Network Mini-Summit, Madison, WI, 2025.
Sturge-Weber syndrome: Neurological complications. Invited Grand Rounds, Michigan State University, 2022.
Juhász C, Luat AF, Keramane H, Behen M.
Imaging markers associated with cognitive and motor functions in Sturge-Weber syndrome: A multivariate analysis in a prospective study. Abstract presentation, International Epilepsy Congress, Lisbon, Portugal, 2025.
Eishi Asano, MD
Johnson EL, Yin Q, Tang L, Asano E, Ofen N. Age-related double dissociation of fast and slow theta oscillations in children and adolescents. Neuromatch 3.0. October 2020. [Virtual meeting]
Yin Q, Johnson EL, Tang L, Auguste KI, Knight RT, Asano E, Ofen N. Direct brain recordings reveal occipital cortex involvement in memory development. Neuromatch 3.0. October 2020. [Virtual meeting]
Kuroda K, Sonoda M, Motoi H, Nariai H, Luat AF, Sood S, Asano E. High-frequency oscillation and phase-amplitude coupling equally improve the prediction of epilepsy surgery outcome. Presented at the 74th Annual
Meeting of the American Epilepsy Society, Seattle, WA, December 2020. [Virtual meeting]
O’Hara NB, Asano E, Juhasz C, Lee MH, Jeong JW. Intracranial propagation trajectories of ictal
fast waves and interictal spikes in patients with epileptic spasms. Presented at the 74th Annual Meeting of the American Epilepsy Society, Seattle, WA, December 2020. [Virtual meeting]
Jeong JW, Lee MH, O’Hara N, Sonoda M, Juhasz C, Asano E. Deep learning of multi-modal MRI improves the localization of seizure onset zone in children with focal epilepsy. Presented at the 74th Annual Meeting of the American Epilepsy Society, Seattle, WA, December 2020. [Virtual meeting]
Latif S, Iwaki H, Asano E. Interviewing as a tool to increase social media engagement with research in clinical neurophysiology. Presented at the 74th Annual Meeting of the American Epilepsy Society, Seattle, WA, December 2020. [Virtual meeting]
Sonoda M, Silverstein BH, Jeong JW, Sugiura A, Nakai Y, Rothermel R, Luat AF, Sood S, Asano E. A novel four-dimensional tractography reveals the development of dynamic effective connectivity supporting specific stages of linguistic processing. Presented at the 74th Annual Meeting of the American Epilepsy Society,
Seattle, WA, December 2020. [Virtual meeting] Selected for the AES2020 Jack M. Pellock Award at the 74th Annual Meeting of the American Epilepsy Society, December 2020; the sole awardee selected from over 1100 submissions.
Iwaki H, Sonoda M, Osawa S, Silverstein BH, Ukishiro K, Takayama Y, Kambara T, Kakinuma K, Suzuki K, Tominaga T, Nakasato N, Iwasaki M, Asano E. Your verbal questions beginning with ‘what’ will rapidly suppress the left prefrontal cortex of listeners. Presented at the 74th Annual Meeting of the American Epilepsy Society, Seattle, WA, December 2020. [Virtual meeting]
Mitsuhashi T, Sonoda M, Iwaki H, Luat AF, Sood S, Asano E. Four-dimensional tractography to animate the interhemispheric effective connectivity. Presented at the 74th Annual Meeting of the American Epilepsy Society, Seattle, WA, December 2020. [Virtual meeting]
Ono H, Sonoda M, Silverstein BH, Sonoda K, Kubota T, Luat AF, Sood S, Asano E. Fourdimensional atlas of saccadic suppression in the human brain. Presented at the 74th Annual Meeting of the American Epilepsy Society, Seattle, WA, December 2020. [Virtual meeting]
Kumar A, Muzik O, Luat A, Asano E, Intikhab O, Malkawi I, Rangunwala J, Sood S, Juhasz C, Chugani HT. Experience from 223 C-11-PK11195 Brain Positron Emission Tomography (PK PET) in Both Pediatric and Adult Population will be Used to Emphasize the Feasibility and Usefulness of PK PET in the Evaluation and Management of Neuroinflammation. Presented at the 106th Annual Meeting of the Radiological Society of North America, Chicago, IL, November and December, 2020. [Virtual meeting]
Dombkowski A, Cukovic D, Ukasic D, Doyon-Real N, Asano E, Jena BP, Chugani H, Stemmer P, Chugani D, Luat A. Exosomes secreted from epileptogenic TSC tubers carry proteins associated with vesicle-mediated transport and seizures. Presented at the 1st North American Epilepsy Congress, Toronto, ON, September 2020. [Virtual meeting]
Lee MH, O’Hara N, Juhasz C, Asano E, Jeong JW. Deep learning of electrical stimulation mapping-driven diffusion tractography to improve preoperative evaluation of pediatric epilepsy surgery. Presented at the 28th Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), Sydney, Australia, August 2020. [Virtual meeting]
Jeong JW, Lee MH, O’Hara N, Asano E, Juhasz C. Deep convolution neural network-based connectome analysis to predict language improvement after pediatric epilepsy surgery. Presented at the 28th Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), Sydney, Australia, August 2020. [Virtual meeting]
Rau E, Johnson EL, Heinen R, Asano E, Ofen N, Axmacher N. Electrophysiological dynamics of visual scene representations in children and adolescents. Accepted for the presentation at the Single Units and Human intracranial (SUsHi) conference, Birmingham, UK, April 2020. [Conference cancelled]
Banerjee S, Dong M, Lee MH, O’Hara N, Asano E, Jeong JW. Prediction of language impairment using deep relational reasoning. Presented at the 2020 IEEE International Symposium on Biomedical Imaging, Iowa City, IA, April 2020. [Virtual meeting]
Principal Investigator: Asano E.
Co-investigator: Luat AF.
Project Title: Functional brain mapping in pediatric neurosurgery.
Funding Agency: NIH.
Project ID: R01 NS064033.
Principal Investigator: Jeong JW.
Co-investigator: Asano E.
Project Title: Novel DWI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery.
Funding Agency: NIH.
Project ID: R01 NS089659.
Principal Investigator: Juhasz C.
Co-investigator: Luat AF.
Project Title: Longitudinal Neuroimaging in Sturge-Weber Syndrome.
Funding Agency: NIH.
Project ID: R01 NS041922.
Principal Investigator: Ofen N.
Co-investigator: Asano E.
Project Title: Development of Memory Networks in Children.
Funding Agency: NIH.
Project ID: R01 MH107512.
Principal Investigator: Waddell WT, Huettemann M, Sanderson TH.
Co-investigator: Asano E.
Project Title: Development and Testing of LUCID: A Therapeutic Device for Brain Injury Following Infant Cardiac Arrest.
Funding Agency: NIH.
Project ID: U44 NS125160.
Principal Investigator: Firestone E.
Mentor: Asano E.
Project Title: Intraoperative Localization of Epileptic Brain Regions Under Sevoflurane Anesthesia.
Funding Agency: NIH.
Project ID: F30. NS129239.
Principal Investigator: O’Hara N.
Mentor: Asano E.
Project Title: Clobazam Adjunctive Therapy in Pediatric Dravet Syndrome
Funding Agency: NIH.
Project ID: F30. NS115279.
Principal Investigator: Dombkowski A.
Co-investigator: Luat AF.
Project Title: Exosome biomarkers of epilepsy in tuberous sclerosis complex patients
Funding Agency: Department of Defense.
Project ID: W81XWH-22-1-0798.
Eishi Asano, MD
Title: Software and Hardware Development for Epileptic Seizure Prediction using Deep Learning Techniques. Agency: Wayne State University Summer 2020 Richard Barber Interdisciplinary Research Program (intramural grant). PI: Mohammad Alhawari, PhD. Co-PI: Eishi Asano, MD, PhD. Direct cost: $35,000. Major goal: The major goal of the project is to design an energy-efficient, accurate, and low-cost automated epilepsy prediction system using intracranial EEG (iEEG) and based on deep learning methods. May 2020-April 2021.
Title: Development of language systems in the human brain. Agency: Wayne State University Grants Boost Program (intramural grant). Application number: 19-1606. PI: Eishi Asano, MD, PhD. Direct cost: $35,000. Major goal: The major goal of the project is to build the first comprehensive model of the maturational changes in language network dynamics that support normative development of proficiency in naming. September 2019-September 2020.
– Title: 3D neonatal photoacoustic tomography (3D-NPAT) to detect hypoxic-ischemic brain injury in preterm neonates. Agency: National Institutes of Health / National Institute of Biomedical Imaging and Bioengineering (NIBIB). National Institute of Neurological Disorders and Stroke (NINDS). Application #: R01EB028661. [PI: Kamran Avanaki, PhD] My role: CoInvestigator (for providing my clinical expertise). Effort: 0.5 months (4.2%). Direct cost: $1,066,792. The major goal is to determine the potential utility of transfontanelle photoacoustic imaging in detection of hypoxic-ischemic brain injury in preterm neonates. Sep 2019 to Sep 2021
Title: The role of non-coding RNAs in epilepsy of tuberous sclerosis complex and focal cortical dysplasia type 2B. Agency: National Institutes of Health / National Institute of Neurological Disorders and Stroke (NINDS). Application #: R56. NS079429. [PI: Alan Dombkowski, PhD] My role: Co-Investigator (for EEG data acquisition and analysis) Effort: 5%. Total amount: $350,000. The goal of this research is to identify non-coding RNAs associated with epileptogenesis in malformations of cortical development. Aug 2019 to Jul 2020
Title: Transfontanelle photoacoustic imaging to study pathophysiology of neonatal brain injury. Agency: National Institutes of Health / National Institute of Biomedical Imaging and Bioengineering (NIBIB). Application #: R01EB027769. [PI: Kamran Avanaki, PhD] My role: CoInvestigator (for providing my clinical expertise). Effort: 0.2 months (1.7%). Direct cost: $1,523,204. Major goal: The major goal is to develop a novel imaging method, referred to as transfontanelle photoacoustic imaging, for accurate detection of neonatal brain injury. Apr 2019 to Dec 2022.
Title: Development of memory networks in children. Agency: National Institutes of Health / National Institute of Mental Health (NIMH). Application #: R01MH107512. [PI: Noa Ofen, PhD] My role: Co-Investigator (for acquisition and analysis of electrocorticography data). Effort: 1.2 months (10%). Direct cost: $1,275,415. Major goal: The major goal of this project is to localize the memory networks in children using electrocorticography and functional MRI. Jun 2016 to Mar 2021.
Title: Novel DWI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery. Agency: National Institutes of Health / National Institute of Neurological Disorders and Stroke (NINDS). Application #: R01NS089659. [PI: Jeong-won Jeong, PhD] My role: CoInvestigator (for acquisition and analysis of stimulation data). Effort: 1.2 months (10%). Direct cost: $1,050,000. Major goal: The major goal of this project is to localize the language areas using functional MRI and diffusion-weighted imaging techniques. Feb 2015 to Dec 2020.
Title: Functional Brain Mapping in Pediatric Neurosurgery. Agency: National Institutes of Health / National Institute of Neurological Disorders and Stroke (NINDS). Application #: R01NS064033. My role: Principal Investigator. Effort: 3.0 months (25%). Direct cost: $1,093,750. The major goal of the project is to determine the efficacy of cortical mapping using electrocorticography for prediction of language outcomes to enhance the safety and success of pediatric brain surgery. Funded with a score of top 1.0 percentile. Mar 2009 to May 2021.
Eishi Asano, MD, PhD
– Executive Guest Editor (2025–2026), NeuroImage — Special Issue on invasive approaches to neural dynamics
– Social Media Editor (2000–2026), Clinical Neurophysiology and Clinical Neurophysiology Practice (Official journals of the International Federation of Clinical Neurophysiology)
– Editorial Board Member (2025–2026), Epilepsia (Official journal of the International League Against Epilepsy)
– Excellence in Research Award (2025), Central Michigan University
– Top Docs Award (2024), Hour Detroit Magazine
Ashlynn Calka, RD
– G. Malcolm Trout Food Science & Human Nutrition Scholarship (2018–2019)
– Beth and Holly Fryer Endowed Scholarship (2017–2018)
– State of Michigan Outstanding Achievement Award (2015)
A.H.M. Mahbubul Huq, MD, PhD
– Research Award for Clinical Trainees, NIH Research Festival
– Miki Koraku Award for Excellence in Research, Tokushima, Japan
– Best Medical Graduate (Gold Medal), Dhaka Medical College
Norimitsu Kuwabara, MD
– Faculty Award for Academic Excellence (2015), University of Hawaii Pediatric Residency Program
– Resident Teaching Award (2014), University of Hawaii Pediatric Residency Program
– Professional Growth Award (2010), U.S. Naval Hospital Okinawa
Aimee F. Luat, MD
– Wayne State University College Teaching Award (2018)
– Physician Difference Maker Award (2018), Children’s Hospital of Michigan
– Outstanding Pediatric Neurology Faculty Award (2025), Wayne State University School of Medicine
– Top Docs Award (2019–2025), Hour Detroit Magazine
Richard L. Smith, MD
– Faculty Teaching Award for Medical Student Education (2019–2024)
– MD with Distinction in Biomedical Research (2018), Wayne State University School of Medicine
Daniela O. Tapos, MD
– Teaching Award, Department of Neurology, Wayne State University (2023)
– Outstanding Pediatric Neurology Faculty Award, Wayne State University School of Medicine (2023)
Carla R. Watson, MD
– Best Child Neurology Attending Physician (2024)
– Child Neurology Society Outstanding Junior Member Award (2017)
– CNS John M. “Jack” Pellock Resident Seminar in Epilepsy Scholarship (2016)
– Neonatology ICU Resident of the Year (2014)
– Marjorie Edwards Prize for Scholarship and Community Service (2012)
Mitchel T. Williams, MD
– Wayne State University School of Medicine Faculty Teaching Award (2019)
– American College of Physicians National Medical Student Abstract Competition Winner (2006)
– Child Neurology Society Outstanding Junior Member Award (2013)
– Pediatric Neurology Trainee Publication Award (2015)
– Top Docs Award (2019–2025), Hour Detroit Magazine
Eishi Asano, MD
Awards:
Social Media Editor in Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology. Apr 2020-present.
Other Professional Accomplishments:
Eishi Asano. Critical appraisal of new investigative tools for epilepsy surgery –Tractography- Invited lecture at the 1st North American Epilepsy Congress, organized by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Toronto, ON, Canada. Sep 25, 2020. [Virtual meeting]
Eishi Asano. Cortical stimulation and brain mapping in extra- and intra-operative epilepsy surgeries. Keynote lecture at the 2020 Cleveland Clinic Epilepsy Update and Review Course, Cleveland, OH. Sep 23, 2020. [Virtual meeting]
Eishi Asano. Scientific session: “How deep in the brain can you see with EEG, MEG and EEGfMRI?” Session Director at the 2020 Annual Meeting of American Clinical Neurophysiology Society, New Orleans, LA, Feb 7-9, 2020.
Eishi Asano. Technical aspects of signal acquisition and planning of stereo-EEG for language mapping. Invited lecture at the 2020 Annual Meeting of American Clinical Neurophysiology Society, New Orleans, LA, Feb 7-9, 2020.
Special Areas of Focus
Refractory Epilepsy
We have a dedicated group of child neurologists who have specialized training in pediatric epilepsy. We discuss complex cases in our weekly epilepsy meetings, recommend resective or palliative surgical interventions and work collaboratively with our neurosurgical colleagues. We have expertise in various devices such as VNS and RNS.
Muscular Dystrophy
We are funded by the Muscular Dystrophy Association of America. We run a comprehensive MDA clinic with participation of neurologists, rehabilitation physicians, occupational and physical therapists and dietitians.
Concussion Clinic
We evaluate children within days of a concussion, coordinate return to school programs and make recommendations for long term care.







