Critical Care
University Pediatricians | Michigan
About the Division of Pediatric Critical Care
The Children’s Hospital of Michigan is southeast Michigan’s major referral center for children who need the most sophisticated medical and surgical care. Many of these patients spend time in the Intensive Care Unit (ICU), which also receives referrals from northern Lower Michigan and the Upper Peninsula. State-of-the-art support and monitoring of critically ill children is available at the bedside.
The intensive care unit is currently a 32-bed unit with 4 additional extension beds available for additional critically-ill or chronically-ventilated patients. There are more than 2000 admissions per year. Admissions to the ICU include but are not limited to acute respiratory failure; fulminant infectious disease and sepsis; traumatic head injury; status epilepticus; oncologic complications including care of children following bone marrow or stem cell transplant; inborn errors of metabolism; and poisonings. The ICU also provides post-operative care following high-risk surgical procedures including neurosurgery, orthopedic spinal surgery, airway reconstruction, surgery for complex congenital heart disease.
Patient Care
The care of the patients is divided between two teams: (1) post-operative cardiovascular surgical and (2) medical and non-cardiac surgical patients. Each team consists of one ICU attending, one or more ICU fellows, and several rotating general pediatric and emergency medicine residents. The post-operative cardiovascular surgical ICU team performs rounds each day with the cardiac surgeons and their staff, providing multi-disciplinary input for these complicated patients. In addition, a pharmacology Ph.D. also attends rounds with each team each day to ensure optimal and safe pharmacologic management.
The Division of Critical Care Medicine provides sedation for a significant number of procedures including but not limited to transesophageal echocardiography, cardioversion, hematologic-oncologic procedures and for critically-ill patients who undergo MRI, CT scan or interventional radiologic procedures.
Leadership
Christian Bauerfeld, MD – Division Chief
Bio coming soon….
Our Team is Dedicated to You
Pediatric Critical Care ICU Attendings
Learn about our University Pediatricians Attendings
Advanced Practice Providers
Want to learn more about our distinguished specialists? Click the button below to be taken to our Faculty Directory.
Education
Critical Care Fellowship Program Director: Ajit Sarnaik, MD
Critical Care Associate Program Director: Ji-Yeon Kim, MD
Children’s Hospital of Michigan is a tertiary care center located in the heart of Detroit. The hospital serves a diverse, urban and suburban population with a vast array of pathology. It is the pediatric facility for the Detroit Medical Center complex and serves as the center for critical care pediatric fellowship training for Central Michigan University. The hospital has accreditation as a Level I Pediatric Trauma Center.
The intensive care unit is currently a 48 bed unit. Admissions to the ICU include but are not limited to acute respiratory failure; fulminant infectious disease and sepsis; traumatic head injury; status epilepticus; oncologic complications including care of children following bone marrow or stem cell transplant; inborn errors of metabolism; and poisonings. The ICU also provides post-operative care following high-risk surgical procedures including heart, liver, and kidney transplant, neurosurgery, orthopedic spinal surgery, airway reconstruction and surgery for complex congenital heart disease.
Although our program is sponsored by Children’s Hospital of Michigan, our fellows are paid via a 501(c)(3) organization, so they are eligible for public service loan forgiveness (PSLF).
Clinical and Research Experience
Children’s Hospital of Michigan is located in an economically and ethnically diverse area that inherently produces a dramatic mix of critical illness. Our fellows get exposure to a wide variety of disease, novel highly specialized therapies as well as a broad spectrum of general pediatric critical illness.
Extensive Training in Cardiovascular Medicine: Having a mixed medical and cardiac unit is advantageous for fellow education as fellows play an integral role in the management of post-operative cardiac surgical patients. At the Children’s Hospital of Michigan, PICU fellows round on these children each day, perform most life-sustaining procedures, and handle most post-operative emergencies alongside the attending. At night, the PICU fellow and attending have primary responsibility for all CV surgery patients. In addition, fellows have rotations through the cardiac catheterization laboratory and cardiovascular surgery operating room during their first year of fellowship.
All PICU fellows will be trained in flexible fiberoptic bronchoscopy. Beginning in their first month, PICU fellows will have access to an advanced flexible bronchoscopy simulator. PICU fellows perfect their skills by performing bronchoscopies during their months of service during which they are trained and mentored by the critical care faculty, who are credentialed in pediatric fiberoptic bronchoscopy.
The use of CVVHDF is becoming increasingly common for the management of critically-ill children with acute renal failure, fluid overload, and sepsis. At the Children’s Hospital of Michigan, primary responsibility for CVVHDF in the PICU lies with the intensive care service, in collaboration with our nephrology service. PICU fellows will become experienced in establishing vascular access, determining prescriptions for the dialysate, replacement fluids, anticoagulation and total dose of CVVHDF. They also become experienced in troubleshooting problems that arise. We are currently using the PrismaFlex® by Gambro for all patients requiring CVVHDF, including those on extracorporeal membrane oxygenation.
Pediatric critical care electives are encouraged. Faculty and fellows have participated in cardiac surgery missions to various locations including the Dominican Republic, Ecuador, and Ukraine.
For more information, please refer to the Pediatric Critical Care Medicine fellowship page on childrensdmc.org—click here or on the button below to visit the site.
Research
The Division of Critical Care Medicine at CHM has been a site for the Collaborative Pediatric Critical Care Research Network (CPCCRN) since its inception in 2005. The CPCCRN is a multicenter program devoted to the investigation of the safety and efficacy of treatment and management strategies used for the care of critically ill and injured children. The CPCCRN at CHM is lead by Dr. Kathleen Meert and funded by the Pediatric Trauma and Critical Illness Branch (PTCIB) of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), a part of the National Institutes of Health (NIH).
The CPCCRN is currently made up of 13 core clinical sites and 12 ancillary sites and a data coordinating center (DCC). The goal of the network is to develop an infrastructure to pursue well-designed collaborative clinical trials and meaningful descriptive studies in pediatric critical care medicine. Working together, the Network has engaged in a number of now completed and ongoing interventional trials. Today our objective is to continue to seek out ways to reduce morbidity and mortality in pediatric critical illness and injury, and to provide a framework for the development of the scientific basis of pediatric critical care practice.
Recent Publications and Recent Areas of Focus
Tageldin Ahmed, MD
Variability in chest compression rate calculation during pediatric cardiopulmonary resuscitation. William P Landis et al. Resuscitation 149 (2020) 127-133.
Christian Bauerfeld, MD
Meert KL, Banks R, Holubkov R, Pollack MM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Morbidity and Mortality in Critically Ill Children. II. A Qualitative Patient-Level Analysis of Pathophysiologies and Potential Therapeutic Solutions. Crit Care Med. 2020 Jun;48(6):799-807. doi: 10.1097/CCM.0000000000004332 Journal Impact Factor: 7.414, Citations:1
Talreja J, Bauerfeld C, Sendler E, Pique-Regi R, Luca F, Samavati L. Derangement of Metabolic and Lysosomal Gene Profiles in Response to Dexamethasone Treatment in Sarcoidosis Front Immunol, 2020 May 12;11:779. doi: 10.3389/fimmu.2020.00779. eCollection 2020Manuscript writing, experimental design Journal Impact Factor: 6.429, Citations: 0
Bauerfeld C, Talwar H, Zhang K, Liu Y, Samavati L. MKP-1 Modulates Mitochondrial Transcription Factors, Oxidative Phosphorylation, and Glycolysis Immunohorizons, 2020 May 15;4(5):245-258. Doi 10.4049/immunohorizons.2000015 Writing manuscript, experimental designs, experiments Journal Impact Factor: unknown, Citations: 0
Siems A, Banks R, Holubkov R, Meert KL, Bauerfeld C, Beyda D, Berg RA, Bulut Y, Burd RS, Carcillo J, Dean JM, Gradidge E, Hall MW, McQuillen PS, Mourani PM, Newth CJL, Notterman DA, Priestley MA, Sapru A, Wessel DL, Yates AR, Zuppa AF, Pollack MM. Structured Chart Review: Assessment of a Structured Chart Review Methodology. Hosp Pediatr. 2020 Jan; 10(1):61-69. doi: 10.1542/hpeds.2019-0225 Site data collection Journal Impact Factor: 0.92, Citation: 3
Heidemann SM, Tilford B, Bauerfeld C, Martin A, Garcia RU, Yagiela L, Sarnaik AP. Three Cases of Pediatric Multisystem Inflammatory Syndrome Associated with COVID-19 Due to SARS-CoV-2 Am J Case Rep 2020; 21:e925779, DOI: 10.12659/AJCR.925779 Manuscript preparation, proof reading Journal Impact Factor: 0.69, Citations: 0
Katherine Cashen, MD
Cashen K, Petersen TL, Rood C, Cater D, Waslawski SF, Slaven J, Mastropietro CW. Emergency Department Utilization After Fontan Palliation. Cardiol Young, 2020; 30 (12): 1902-1909. PMID 3312155
Radman M, Mastropietro CW, Amula V, Caudill E, Costello JM, Flores S, Karki K, Migally K, Narasimhulu S, Piggott K, Sassalos P, Wilhelm M, Cashen K and the Collaborative Research from the Pediatric Cardiac Intensive Care Society (CoRe-PCICS) Investigators. Multicenter Analysis of Intermediate Outcomes after Repair of Anomalous Left Coronary Artery from the Pulmonary Artery. Ann Thorac Surg 2020; S0003-4975 (20)31500-9. PMID: 32961142
Kwiatowski D, Mastropietro CW, Cashen K, Chiwane S, Flores S, Iliopoulos I, Karki K, Migally K, Radman MR, Riley CM, Sassalos P, Smerling J, Costello J. Collaborative Research from the Pediatric Cardiac Intensive Care Society (CoRe-PCICS) Investigators. Presentation and surgical outcomes of patients with anomalous left coronary artery from the pulmonary artery diagnosed after one year of age: a multicenter study [published online ahead of print August 25,2020]. Sem Thorac Cardiovasc Surg, PMID: 32858217
Bakar AM, Costello JM, Sassalos P, Amula V, Buckley JR, Smerling AJ, Iliopoulos I, Riley CM, Jennings A, Cashen K, Suguna Narasimhulu S, Narayana Gowda KM, Wilhelm M, Badheka A, Slaven JE, Mastropietro CW; Collaborative Research from the Pediatric Cardiac Intensive Care Society (CoRe-PCICS) Investigators. Multicenter Analysis of Truncal Valve Management and Outcomes in Children with Truncus Arteriosus. Pediatr Cardiol 2020;41(7):1473-1483. PMID: 32620981
Cashen K, Dalton HD, Reeder R, Saini A, Zuppa AF, Shanley TP, Newth CJ, Pollack MM, Wessel D, Carcillo J, Harrison R, Dean JM, Meert KL. Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Platelet Transfusion Practice and Related Outcomes in Pediatric Extracorporeal Membrane Oxygenation. Pediatr Crit Care Med 2020; 21(2):178-185. PMID: 31568245
Cashen K, Martin A. Platelet Dysfunction during Pediatric Cardiac ECMO. Prog Pediatr Cardiol 2020; 56:101187.
Cashen K, Meert KM, Dalton HD. Platelet Count and Function during Pediatric Extracorporeal Membrane Oxygenation. Semin Thromb Hemost 2020; 46(3):357-365. PMID: 32232826
Richard Garcia, MD
Garcia RU, Meert K, Safa R, and Aggarwal S. Inferior Vena Cava Collapsibility Index to Assess Central Venous Pressure in Perioperative Period Following Cardiac Surgery in Children. Recently accepted for Publication in journal “Pediatric Cardiology”.
Torpoco, D, Garcia RU, Aggarwal S. Vasoactive-ventilation-renal score: a reliable prognostic index for perioperative outcomes following congenital heart surgery in adults. Cardiol Young. 2020 Dec 17;1-7. doi: 10.1017/S1047951120004588. Online ahead of print.
Garcia RU, Balakrishnan PL, and Aggarwal S. Does obesity affect the short-term outcomes after cardiothoracic surgery in adolescents with congenital heart disease?. Cardiol Young. 2020 Mar; 30(3):372-376.
Sabrina M Heidemann, Bradley Tilford, Christian Bauerfeld, Amarilis Martin, Richard U Garcia, Lauren Yagiela, Ashok P Sarnaik Three Cases of Pediatric Multisystem Inflammatory Syndrome Associated with COVID-19 Due to SARS-CoV-2. Am J Case Rep. 2020 Aug 13;21:e925779.
Yu-shan Tseng and Richard U. Garcia (2020). A 5-Year-Old with Altered Mental Status. In: Kline-Tilford, A. and Haut, C. Cases in Pediatric Acute Care: Strengthening Clinical Decision Making. Hoboken: Wiley.
Mina Hafzalah, MD
Abstract S44: Select Abstracts From Cardiology 2020: 23rd Annual Update on Pediatric and Congenital Cardiovascular Disease. (2020). World Journal for Pediatric and Congenital Heart Surgery, 11(2), NP1–NP77
Sabrina Heidemann, MD
Three Cases of Pediatric Multisystem Inflammatory Syndrome Associated with COVID-19 Due to SARS-CoV-2. Heidemann SM, Tilford B, Bauerfeld C, Martin A, Garcia RU, Yagiela L, Sarnaik AP. Am J Case Rep. 2020 Aug 13;21:e925779. doi: 10.12659/AJCR.925779. PMID: 32790652
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. Feldstein LR, Rose EB, Horwitz SM, Collins JP, Newhams MM, Son MBF, Newburger JW, Kleinman LC, Heidemann SM, Martin AA, Singh AR, Li S, Tarquinio KM, Jaggi P, Oster ME, Zackai SP, Gillen J, Ratner AJ, Walsh RF, Fitzgerald JC, Keenaghan MA, Alharash H, Doymaz S, Clouser KN, Giuliano JS Jr, Gupta A, Parker RM, Maddux AB, Havalad V, Ramsingh S, Bukulmez H, Bradford TT, Smith LS, Tenforde MW, Carroll CL, Riggs BJ, Gertz SJ, Daube A, Lansell A, Coronado Munoz A, Hobbs CV, Marohn KL, Halasa NB, Patel MM, Randolph AG; Overcoming COVID-19 Investigators; CDC COVID-19 Response Team. N Engl J Med. 2020 Jul 23;383(4):334-346. doi: 10.1056/NEJMoa2021680. Epub 2020 Jun 29. PMID: 32598831
Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, Heidemann SM, Kleinman LC, Sen AI, Hall MW, Priestley MA, McGuire JK, Boukas K, Sharron MP, Burns JP; International COVID-19 PICU Collaborative. JAMA Pediatr. 2020 Sep 1;174(9):868-873. doi: 10.1001/jamapediatrics.2020.1948. PMID: 32392288
Ji-Yeon Kim, MD
Kim, J and Meert, K. Pediatric Pneumonia with Pleural Effusion. Cases in Pediatric Acute Care: Strengthening Critical Thinking Skills. Hoboken, NJ: Wiley Publishing Company
Kathleen Meert, MD
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth C, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen P, Mourani P, Wong H, Chima R, Doctor A, Willson D, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder R, for the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Trajectory of Mortality and Health Related Quality of Life Morbidity following Community–Acquired Pediatric Septic Shock. Crit Care Med 2020; 48:329-337. PMC7164680
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth C, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen P, Mourani P, Wong H, Chima R, Doctor A, Willson D, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder R, for the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Critical Illness Factors Associated with Long-Term Mortality and Health Related Quality of Life Morbidity following Community–Acquired Pediatric Septic Shock. Crit Care Med 2020; 48:319-328.PMC7089387
Siems A, Banks R, Holubkov R, Meert KL, Pollack MM and the NICHD Collaborative Pediatric Critical Care Research Network. Structured Chart Review: Assessment of a Generalizable Methodology. Hosp Pediatr 2020; 10:61-69. PMC6931034
Landis WP, Morgan RW, Reeder RW, Graham K, Siems A, Diddle J, Pollack MM, Maa T, Fernandez RP, Yates A, Tilford B, Ahmed T, Meert KL, Schneiter C, Bishop R, Mourani PM, Naim M, Friess S, Burns C, Manga A, Franzon D, Tabbutt S, McQuillen PS, Horvar C, Bochkoris M, Carcillo JA, Huard L, Federman M, Sapru A, Viteri S, Hehir DA, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Wolfe HA, Sutton RM, and the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN), and the NHLBI ICU-RESUScitation Project Investigators. Variability in Chest Compression Rate Calculations during Cardiopulmonary Resuscitation. Resuscitation 2020; 149:127-133. PMC7296394
Holzemer NF, Hasvold JJ, Pohl KJ, Ashbrook MJ, Meert KL, Quasney MW. Severe Human Metapneumovirus Infection in Hospitalized Children. Respiratory Care 2020; 65:650-657.
Laudato N, Yagiela L, Eggly L, Meert KL. Understanding Parents’ Informational Needs in the Pediatric Intensive Care Unit. Progress in Pediatric Cardiology 2020; 57: 101172.
Berger JT, Maddux AB, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MP, Sapru A, Yates AR, Notterman DA, Holubkov R Tamburro RF, Dean JM, Wessel D, for the NICHD Collaborative Pediatric Critical Care Research Network. Inhaled Nitric Oxide Use in Pediatric Hypoxemic Respiratory Failure. Pediatr Crit Care Med 2020; 21:708-719. PMC7416469
Morgan RW, Reeder RW, Meert KL, Telford R, Yates AR, Berger JT, Graham K, Landis WP, Kilbaugh TJ, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman D, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Sutton RM, for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN) and Pediatric Intensive Care Quality of Cardio-Pulmonary Resuscitation (PICqCPR) Investigators. Survival and Hemodynamics during Pediatric Cardiopulmonary Resuscitation for Bradycardia and Poor Perfusion Versus Pulseless Cardiac Arrest. Crit Care Med 2020; 48:881-889.
Workman JK, Bailly DK, Reeder RW, Dalton HJ, Berg RA, Shanley TP, Newth CJL, Pollack MM, Wessel D, Carcillo J, Harrison R, Dean JM, Meert KL, for the NICHD Collaborative Pediatric Critical Care Research Network. Risk Factors for Mortality in Pediatric Septic Shock Supported with Extracorporeal Membrane Oxygenation. ASAIO 2020; 66:1152-1160. PMC7773130
Meert KL, Reeder R, Maddux A, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland J, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life after Pediatric Community-Acquired Septic Shock. Pediatr Crit Care Med 2020; 21:869-878.
Pollack MM, Banks R, Holubkov R, Meert KL, and the NICHD Collaborative Pediatric Critical Care Research Network. Morbidity and Mortality in Critically Ill Children, I. Pathophysiologies and Potential Therapeutic Solutions. Crit Care Med 2020; 48:790-798. PMC7242139
Meert KL, Banks R, Holubkov R, Pollack MM, and the NICHD Collaborative Pediatric Critical Care Research Network. Morbidity and Mortality in Critically Ill Children. II. A Qualitative Patient-Level Analysis of Pathophysiologies and Potential Therapeutic Solutions. Crit Care Med 2020; 48:799-807. PMC7242160
Fink EL, Jarvis JM, Maddux AB, Pinto N, Galyean P, Olson LM, Zickmund S, Ringwood M, Sorenson S, Dean JM, Carcillo JA, Berg RA, Zuppa A, Pollack MM, Meert KL, Hall MW, Sapru A, McQuillen PS, Mourani PS, Watson RS, for the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Long-term Outcomes Subgroup Investigators, and the Eunice Kennedy Shriver NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN). Development of a Core Outcome Set for Pediatric Critical Care Outcomes Research. Contemp Clin Trials 2020; 91:105968 PMC7313715
Murphy LK, Palermo TM, Meert KL, Reeder R, Dean JM, Banks R, Berg RA, Carcillo JA, Chima R, McGalliard J, Haaland W, Holubkov R, Mourani P, Pollack M, Sapru A, Sorenson S, Varni JW, Zimmerman J, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Longitudinal Trajectories of Caregiver Distress and Family Functioning after Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med 2020; 21:787-796.
Starr MC, Banks R, Reeder RW, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack M, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima R, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Hingorani S, Zimmerman JJ, for the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Death and New Morbidity Associated with Severe Acute Kidney Injury During Pediatric Septic Shock. Pediatr Crit Care Med 2020; 21:e686-e695. PMC7483282
Wolfe H, Morgan R, Sutton RM, Reeder RW, Meert KL, Pollack MM, Yates AR, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Carpenter TC, Notterman DA, Dean JM, Nadkarni VM, Berg RA for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN). Association between Time of Day and CPR Quality as Measured by CPR Hemodynamics during Pediatric In-hospital CPR. Resuscitation 2020; 153:209-216. PMC7431912
Maddux AB, Pinto N, Fink EL, Hartman ME, Nett S, Biagas K, Killien EY, Dervan LA, Christie LM, Luckett PM, Loftis L, Lackey M, Ringwood M, Smith M, Olson L, Sorenson S, Meert KL, Notterman DA, Pollack MM, Mourani PM, Watson RS, for the POST-PICU and PICUCOS Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators and the Collaborative Pediatric Critical Care Research Network (CPCCRN). Post-discharge outcome domains in pediatric critical care and the instruments used to evaluate them: A scoping review. Crit Care Med 2020; 48:e1313-e1321. PMC7708523
Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN). Therapeutic Alliance between Bereaved Parents and Physicians in the Pediatric Intensive Care Unit. Pediatr Crit Care Med 2020 Oct 9. doi: 10.1097/PCC.0000000000002585. Online ahead of print.
Pollack MM, Banks R, Holubkov R, Meert KL, and the NICHD Collaborative Pediatric Critical Care Research Network. Long-Term Outcome of PICU Patients Discharged with New, Functional Status Morbidity. Pediatr Crit Care Med 2020 Oct 7. doi: 10.1097/PCC.0000000000002590. Online ahead of print.
Wong HR, Reeder RW, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, McQuillen PS, Mourani PM, Chima R, Doctor A, Zimmerman JJ, for the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Biomarkers for Estimating the Risk of Long Term Functional Morbidity after Surviving Pediatric Septic Shock: A Secondary Analysis of the LAPSE Investigation. Pediatr Crit Care Med 2020 Sep 29. doi:10.1097/PCC.0000000000002572. Online ahead of print.
Winder M, Furlong-Dillard JM, Lavering M, Barbaro RP, Meert KL, Bratton SL, Dalton H, Reeder RW, Bailly DK. External Validation of the Pediatric Extracorporeal Membrane Oxygenation Prediction (PEP) Model for Risk Adjusting Mortality. Perfusion 2020 Aug 29; 267659120952979. doi: 10.1177/0267659120952979. Online ahead of print
Fink EL, Maddux A, Pinto N, Sorenson S, Notterman D, Dean JM, Carcillo JA, Berg Ra, Zuppa A, Pollack MM, Meert KL, Hall MW, Sapru A, McQuillen PS, Mourani PM, Amey D, Argent A, Brunow de Carvalho W, Butt W, Choong K, Curley MAQ, del Pilar Arias Lopez, M, Demirkol D, Grosskreuz R, Houtrow AJ, Knoester H, Hau Lee J, Long D, Manning J, Cert PG, Morrow B, Sankar J, Slomine B, Olson LM, Watson RS, the POST-PICU Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN). A Core Outcome Set for Pediatric Critical Care. Crit Care Med 2020; 48:1819-1828
Mourani PM, Sontag MK, Williamson KM, Harris JK, Reeder R, Locandro C, Carpenter TC, Maddux AB, Ziegler K, Simoes E, Osborne CM, Ambroggio K, Leroue MK, Robertson CE, Langelier C, DeRisi JL, Kamm J, Hall MW, Zuppa A, Carcillo J, Meert K, Sapru A, Pollack M, McQuillen P. Notterman DA, Dean JM, Wagner BD, for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN). Temporal Airway Microbiome Changes Related to Ventilator Associated Pneumonia in Children. Eur Respir J 2020 Oct 2;2001829. doi: 10.1183/13993003.01829-2020. Online ahead of print.
Meert KL, Reeder RW, Maddux AB, Banks R, Berg RA, Newth CJ, Hall MW, Quasney M, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, McGalliard J, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Health-Related Quality of Life after Community-Acquired Septic Shock in Children with Pre-existing Severe Developmental Disabilities. Pediatr Crit Care Med 2020 Nov 6. doi: 10.1097/PCC.0000000000002606. Online ahead of print.
Cashen K, Meert K, Dalton H. Platelet Count and Function during Pediatric Extracorporeal Membrane Oxygenation. Semin Thromb Hemost. 2020;46:357-365.
Yagiela L, Meert KL. Informing Future Care Delivery Models through Exploring Isolation in Parents and Providers of Children with Chronic Critical Illness. Pediatr Crit Care Med 2020;21:778-779.
Andrew Prout, MD
Hennon T, Penque M, Abdul-Aziz R, Alibrahim O, McGreevy M, Prout A, Schaefer B, Ambrusko S, Pastore J, Turkovich S, Gomez-Duarte O, Hicar M. COVID-19 associated Multisystem Inflammatory Syndrome in Children (MIS-C) guidelines; a Western New York approach. Progress in Pediatric Cardiology 2020 57
Martone G, Nanjireddy P, Craig R, Prout A, et al. Acute hepatic encephalopathy and multiorgan failure in sickle cell disease and COVID-19 (accepted for publication, Pediatric Blood and Cancer)
Lauren Yagiela, MD
Laudato N, Yagiela L, Meert K. Understanding parents’ informational needs in the pediatric intensive care unit: A Qualitative Study. Progress in Pediatric Cardiology 2020; 57:101172.
Yagiela L, Meert K. Informing future care delivery models through exploring isolation in parents and providers of children with chronic critical illness. Pediatric Critical Care Medicine 2020; 21: 778-779
Maddux AB and Pinto N (joint first authors), Fink EL, Hartman ME, Nett S, Biagas K, Killien EY, Dervan LA,
Christie LM, Luckett PM, Loftis L, Lackey M, Ringwood M, Smith M, Olson L, Sorenson S, Meert KL, Notterman DA, Pollack MM, Mourani PM, Watson RS for Pediatric Outcomes STudies after PICU (POST-PICU) (Yagiela L) and PICU-COS Investigators of thePediatric Acute Lung Injury and Sepsis Investigators and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Networks. Post-discharge outcome domains in pediatric critical care and the instruments used to evaluate them: A scoping review. Critical Care Medicine 2020. Online ahead of print.
Heidemann S, Tilford B, Bauerfeld C, Martin A, Garcia R, Yagiela L, Sarnaik A.Three Cases of Pediatric Multisystem Inflammatory Syndrome Associated with COVID-19 Due to SARS-CoV-2. Am J Case Rep, 2020; 21: e925779
Christian Bauerfeld, MD
Dmitry Davydov, MD, Amarilis Martin, MD and Christian Bauerfeld, MD Detrimental effects of internet-promoted “healthy” homemade formula in two infants. AAP meeting October 2020; Abstract P0456
Katherine Cashen, MD
Martin A, Cashen K, Yagiela L, Tilford B. Severe Refractory Lactic Acidosis Treated with Thiamine and Levocarnitine in a child with malignancy. Crit Care Med 2020; 48(1) 207.
Martin A, Rycus P, Cashen K. ECMO Outcome in Children with Williams Syndrome: A review of the ELSO Registry. Crit Care Med 2020; 48(1) 100
Kim JY, Sarnaik A, Farooqi A, Cashen K. Contemporary Feeding Practices in Postoperative Patients with Congenital Heart Disease. Crit Care Med 2020; 48(1):66
Cashen K. ECMO: A viable option in SARS COVID-2 Pandemic. Oral presentation at the Society of Critical Care Medicine Midwest Chapter Virtual Conference. August, 2020.
Radman M, Mastropietro CW, Costello JM, Amula V, Flores S, Caudill E, Karki K, Migally K, Narasimhulu S, Piggott K, Sassalos P, Wilhelm M, Moser EA, Cashen K. Intermediate Outcomes after ALCAPA Repair. Society of Thoracic Surgery International Meeting January 2020; New Orleans, LA.
Noble J, Kagithala S, Haslitt D, DeLaroche A, Cashen K. Adult rapid response events in a Children’s Hospital. American Academy of Pediatrics Virtual National Conference and Exhibition. 2020
Martin A, Cashen K, Yagiela L, Tilford B. Severe Refractory Lactic Acidosis Treated with Thiamine and Levocarnitine in a child with malignancy. Society of Critical Care Medicine International Meeting. February 2020; Orlando, FL.
Martin A, Rycus P, Cashen K. ECMO Outcome in Children with Williams Syndrome: A review of the ELSO Registry. Society of Critical Care Medicine International Meeting. February 2020; Orlando, FL
Kim JY, Sarnaik A, Farooqi A, Cashen K. Contemporary Feeding Practices in Postoperative Patients with Congenital Heart Disease. Society of Critical Care Medicine International Meeting. February 2020; Orlando, FL
Richard Garcia Soriano, MD
Doctor P, Aggarwal S, and Garcia, RU. Is Near Infrared Spectroscopy Associated with Low Cardiac Output and Adverse Outcomes in Single Ventricle Patients after Stage I Palliation? National Annual PC4 Conference Ann Arbor, Michigan. November 19th 2020
Garcia R, Meert K, Safa R, and Aggarwal S. Inferior Vena Cava Collapsibility Index to Assess Central Venous Pressure in Perioperative Period Following Cardiac Surgery in Children. The Pediatric Cardiac Intensive Care Society 16th International Conference. Miami, Florida December 9-11th 2020
Ji-Yeon Kim, MD
Contemporary Feeding Practices in Postoperative Patients with Congenital Heart Disease Principal investigator for clinical research on assessing current nutritional practices in postop patients with CHD 2020 SCCM Conference Presentation
Kathleen Meert, MD
Morgan RW, Berg RA, Reeder RW, Meert KL, Yates AR, Landis WP, Graham K, Locandro C, Telford R, Tilford B, Wolfe HA, Nadkarni VM, Sutton RM for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN), and the NHLBI ICU-RESUScitation Project Investigators. Hemodynamic Response to Epinephrine during Pediatric Cardiac Arrest is Associated with Outcome. Presented at the Society of Critical Care Medicine Meeting, Orlando, FL, 2/2020.
Morgan RW, Telford R, Reeder RW, Meert KL, Yates AR, Graham K, Landis WP, Kilbaugh TJ, Nadkarni VM, Berg RA, Sutton RM, NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN), and the Pediatric Intensive Care Quality of Cardio-Pulmonary Resuscitation (PICqCPR) Investigators. Hemodynamics during Cardiopulmonary Resuscitation for Bradycardia with Poor Perfusion. Presented at the Society of Critical Care Medicine Meeting, Orlando, FL, 2/2020.
Pollack M, Banks R, Holukov R, Meert KL for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN). Morbidity & Mortality in Critically Ill Children. Part I. Pathophysiologies and Potential Therapies. Presented at the Society of Critical Care Medicine Meeting, Orlando, FL, 2/2020.
Meert KL, Banks R, Holukov R, Pollack M for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN). Morbidity & Mortality in Critically Ill Children. Part II. Details derived from Individual Patients. Presented at the Society of Critical Care Medicine Meeting, Orlando, FL, 2/2020.
Pawluszka A, Coleman W, Suttle M, McKenzie A, Beers S, Willey R, Grosskreuz R, October T, DiLiberto AM, Amey D, Meert KL, Hall M, Mourani P, Berg R, Zuppa A, Wessel D, Pollack M, Carcillo J, McQuillen P, Fink E. CPCCRN Family Network Collaborative: Engaging Families in Pediatric Critical Care Research. Presented at the Society of Critical Care Medicine Meeting, Orlando, FL, 2/2020.
Wolfe HA, Sutton RM, Reeder RW, Meert KL, Pollack MM, Yates AR, Berger JT, Newth CJL, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN) Pediatric Intensive Care Quality of Cardiopulmonary Resuscitation (PICqCPR) Investigators. Cardiopulmonary Resuscitation Quality Measured by Diastolic Blood Pressure during Day versus Night. Presented at the Society of Critical Care Medicine Meeting, Orlando, FL, 2/2020.
Leroue MK, Curtin P, Sontag MK, Williamson KM, Wagner BD, Ambroggio L, Bixby M, Busgang S, Murphy SE, Peterson LA, Vevang KR, Sipe CJ, Tang MK, Harris JK, Reeder R, Locandro C, Carpenter TC, Maddux AB, Simoes E, Osborne CM, Ziegler K, Robertson CE, Langelier C, KammJ, DeRisi JL, Hall MW, Zuppa A, Carcillo J, Meert K, Sapru A, Pollack M, McQuillen P, Nottingham DA, Mourani PM, for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN). The Relationship of Tobacco Smoke Exposure on the Lower Airways Microbiome and Clinical Outcomes of Critically Ill, Mechanically Ventilated Pediatric Patients. Accepted to the Pediatric Academic Societies Meeting, Philadelphia, PA, 4/2020. (Meeting canceled due to COVID).
Suttle M, Hall MW, Pollack MM, Berg R, McQuillen PS, Mourani P, Sapru A, CArcillo J, Startup E, Holubkov R, Notternam DA, Meert K. Therapeutic Alliance between Bereaved Parents and Physicians in the Pediatric Intensive Care Unit (PICU). Accepted to the Pediatric Academic Societies Meeting, Philadelphia, PA, 4/2020. (Meeting canceled due to COVID).
Fink E, Maddux A, Pinto N, Carcillo J, Berg R, Zuppa A, Pollack M, Meert K, Hall M, Sapru A, McQuillen P, Mourani P, Dean J, Notterman D, Smith M, Sorenson S, Ringwood M, Houtrow A, Long D, Carvalho W, Demirkol D, Knoester H, Sankar J, Manning J, Argent A, Choong K, Slomine B, Lee JH, Arias Lopez M, Grosskreuz R, Butts W, Curley M, Amey D, Morrows B, Olson L, Watson RS. A Core Outcome Set for Pediatric Critical Care Research. Accepted to World Federation of Pediatric Intensive and Critical Care Society (WFPICCS), Mexico City, Mexico, 6/2020.
Garcia R, Meert K, Safa R, Aggarwal S. Noninvasive measurement of CVP after cardiac surgery. Pediatric Cardiac Intensive Care Society 16th Annual Meeting. Miami, FL, 12/2020.
Miya T, Furlong-Dillard J, Sizemore J, Meert K, Dalton H, Reeder R, Bailly D. The Association of Ventilator Settings and Mortality among Pediatric Patients receiving Extracorporeal Membrane Oxygenation for Respiratory Failure. 31st Annual ELSO Virtual Conference, 9/2020
Andrew Prout, MD
Isoflurane for Near-Fatal Asthma Complicated by Malignant Hyperthermia (abstract accepted at Society of Critical Care Medicine, co-author)
High Dose Insulin for Calcium Channel Blocker Overdose In A Pediatric Patient (abstract accepted at Society of Critical Care Medicine, co-author)
Ajit Sarnaik, MD
“Contemporary Feeding Practices in Postoperative Patients With Congenital Heart Disease,” Society of Critical Care Medicine 49th Annual Congress. Role: co-author, mentor (Dr. Ji-Yeon Kim was 1st author and presenter) Feb 2020
Lauren Yagiela, MD
Case Report: SCCM abstract / presentation Martin A, Cashen K, Yagiela L, Tilford B Title: Severe Refractory Lactic Acidosis Treated with Thiamine and Levocarnitine in a Child with Malignancy
Jamie Bell, MD
Children’s Hospital Foundation 05/01/2019-05/01/2021
Functional Recovery after Kidney Ischemia/Reperfusion Injury: Non-Invasive Application of Specific Wavelength Infra-red Light
Katherine Cashen, MD
Title: “ARDS in Children and ECMO Initiation Strategies Impact on NeuroDevelopment (ASCEND)” Role: Site Principal Investigator, Percent Effort: 5%
PI: Barbaro Source: NIH RO1 Date 7/2020 Total Direct Costs: $14,400
Sabrina Heidemann, MD
Understanding COVID-19 among critically ill children in the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network $54,750 (subcontract under a federal contract with The Children’s Hospital Corporation d/b/a Boston Children’s Hospital).
Kathleen Meert, MD
NIH/National Institute of Child Health and Development: UG1HD050096 Collaborative Pediatric Critical Care Research Network. PI: K. Meert, MD 2005-2020
NIH/National Heart Lung Blood Institute: R01HL131544 Improving Outcomes After Pediatric Cardiac Arrest. PI: R. Sutton; Children’s Hospital of Philadelphia. Dr. Meert is a site investigator. 2016-2021
Ajit Sarnaik, MD
Role: Site PI (Main PI: Bradley Kurowski, M.D. Cincinnati Children’s Hospital Medical Center) R01 NS096053-01A1
Title: “Genetic and Environmental Influences on Recovery of Severe Pediatric Brain Injury” This multi-center, prospective and retrospective observational cohort study of children with severe TBI aims to identify associations between genetic variants on recovery of global, neurocognitive, and behavioral functioning following severe pediatric TBI. Of the 25 patients our site enrolled from the ADAPT Trial (see below), I am currently enrolling and collecting DNA samples Source: NIH/NINDS Status: Active, 2017-current
Lauren Yagiela, MD
K12 Pediatric Critical Care and Trauma Scientist Development Program (Funds: $223,769)
Kathleen Meert, MD
2020 Fellow, Central Michigan University Academy of Medical Educators
2020 Top Docs – Detroit Hour magazine
2020 Schotanus Family Endowed Chair of Pediatrics
Andrew Prout, MD
Awards:
2020 Faculty Teaching Award, UBMD Department of Pediatrics
Other Professional Accomplishments:
Resident education coordinator, Division of Pediatric Critical Care Central-Line Associated Bloodstream Infection committee member, Children’s Hospital of Michigan
Jamie Bell, MD
Other Professional Accomplishments:
Interim Pediatric Critical Care Fellowship Program Director August 2020-October 2020 Pediatric
Critical Care Fellowship Associate Program Director November 2020 – present
Katherine Cashen, MD
Other Professional Accomplishments:
Cashen K. Guest Speaker. “COVID-19 and Multisystem Inflammatory Syndrome in Children (MIS-C)” Pediatric Cardiac Intensive Care Society Podcast. Aired: July 30, 2020. https://podcasts.apple.com/us/podcast/episode-25-covid-19-multisystem-inflammatorysyndrome/id1253068670
Mina Hafzalah, MD
Other Professional Accomplishments:
CHM/CMU: ACTION network. Member and Site Principal Investigator for ACTION.