Allergy, Asthma, Immunology, and Rheumatology
University Pediatricians | Michigan
About the Division of Allergy, Asthma, Immunology, and Rheumatology
The Allergy, Asthma and Immunology Division at Children’s Hospital of Michigan at the Detroit Medical Center has a long history of excellence in care for asthmatic, allergic and immune deficient children.
The division offers evaluation and treatment for asthma and a wide range of allergies, including food allergy, environmental allergy, drug and vaccine allergy, insect sting allergy, angioedema, anaphylaxis, hives, eczema and other allergic skin conditions. Advance treatment plans are available for your specific conditions including allergen immunotherapy and monoclonal antibody treatment.
The high risk asthma clinic is supported by a grant from Children’s Hospital Foundation offering medical and psychosocial support to children with severe and/or high risk asthma. Research studies with emphasis on assistance with adherence to medication and identification of stressors that influence asthma are available to those clients, and any other interested families with asthmatics.
The asthma and allergy physicians on the medical staff and asthma nurse educators see every asthmatic patient admitted to the Children’s Hospital of Michigan. This assures that all asthmatic children and families are offered the highest standard of care for their asthma, with particular emphasis to follow-up daily care, education, and action planning.
Pavadee Poowuttikul, MD – Division Chief
The Chief of Allergy, Asthma, Immunology and Rheumatology Division, Pavadee Poowuttikul, MD, along with six board certified allergists/immunologists and two board certified pediatric rheumatologist, all have faculty appointments at Central Michigan University College of Medicine. All faculty are actively involved in teaching medical students from Central Michigan University and Wayne State University, pediatric and internal medicine residents, and allergy/immunology fellows. The division also includes specialized allergy/immunology/rheumatology nurse practitioners, nurses, and social workers.
The focus of the Allergy, Asthma, Immunology and Rheumatology Division at the Children’s Hospital of Michigan is to:
Our Clinical Programs
Pediatric Rheumatology Section
We offer a rheumatology clinic and vasculitis clinic for children and adolescents. Conditions evaluated and treated include childhood autoimmune diseases such as juvenile idiopathic arthritis, systemic lupus erythematosus, vasculitis and juvenile dermatomyositis; and autoinflammatory disorders such as periodic fever syndromes, and autoinflammatory disorders of the bones.
Immunology Section
We offer a Primary Immune Deficiency Clinic for children and adults, diagnosing and treating a range of conditions including agammaglobulinemia, CVID, IgA deficiency, SCID, and more. We also serve as a referral center for complex immune system disorders and coordinate Michigan’s Primary Immunodeficiency Newborn Screening Center.
Asthma, Allergy and Immunology Section
We treat children and adults with asthma and a wide range of allergic conditions, including food, environmental, drug, and insect allergies, as well as eczema, hives, and anaphylaxis. Our clinic offers evaluations, in-office testing (pulmonary function, FeNO, and skin tests), and advanced treatments like allergen immunotherapy, oral immunotherapy, and monoclonal antibody therapy. Research study opportunities are also available.
Our faculty are familiar with the most recent advances and recommendations in the management of allergic, immunologic, and rheumatologic conditions and offer comprehensive and patient-centered services geared towards their diagnosis and treatment. The team of dedicated nurses work on obtaining prior authorizations for expensive medications deemed necessary for management of the patients in order to provide them the most cost-effective therapy. Outpatient appointments are available Monday-Friday and some Saturdays. Same-day appointments are available for patients requiring urgent evaluations.
Our Specialized Clinics Include
Only about 10% of patients who believe they are allergic to penicillin truly are. Labeling patients “allergic” when they are not can cause a burden both for patients and our health care system. Patients may not be able to get a first-line drug for treatment, leading to the use of more expensive antibiotics, and the risk of developing antibiotic resistant infections.
We offer a Drug Allergy Procedures Clinic focused on testing for drug allergies. Patients will have an initial evaluation to determine if the test and/or challenges are appropriate and will be referred to the Drug Allergy Procedures Clinic if needed. In this clinic, patients will either complete extensive allergy skin testing, undergo a direct oral challenge or both, under close supervision. Following a period of observation, the patient’s drug allergy will either be confirmed or can be safely removed from the allergy list.
We also provide an evaluation for aspirin allergy and aspirin desensitization for patients with Aspirin-Exacerbated Respiratory Disease (AERD). Other medication challenges are also possible depending on the types of the reactions. Venom testing for patients with an insect sting allergy is also available.
Food allergies affect ~6 million children in the U.S. Symptoms of food allergy range from mild to life threatening. Many children will outgrow a food allergy. The Allergy and Immunology Division at Children’s Hospital of Michigan helps patients find out if they have outgrown a food allergy or if the patient is truly allergic to certain foods. Once the patient is evaluated during the initial clinic visit and determined that an oral food challenge is indicated, the patient will be referred to the Food Challenge Clinic. During the Food Challenge Clinic, the reintroduction of the food will be performed under close monitoring. Each oral food challenge appointment takes approximately four hours, as the food will be introduced gradually. A successful food challenge confirms that the patient has outgrown the food allergy and the food can be safely reintroduced into their regular diet. While allergy testing alone can fail to define food tolerance, oral food challenges provide an effective and definitive way to rule out food allergy. We also perform evaluation and early introduction of allergenic foods to infants who may be at high risk. allergenic foods patients, who are qualified for allergenic foods oral immunotherapy (OIT), will be offered this therapy and receive their initial doses of allergenic foods in the Food Challenge Clinic as well.
The high-risk asthma clinic offers comprehensive medical and psychosocial support to children with severe, difficult-to-control and/or high-risk asthma. Research studies with an emphasis on adherence to medication and identification of stressors are available to patients with asthma and interested families. The program involves a multidisciplinary team, including asthma/allergy specialist, asthma nurse educator, and social worker, that assists in addressing treatment barriers and comorbid conditions that can contribute to asthma severity. We take a patient centered approach to improve asthma control and the quality of life of our patients and families with particular emphasis on follow-up, daily care, asthma control, asthma education, and action planning. Our goal is to work with families to help minimize the effect of asthma on children by creating detailed treatment plans to prevent symptoms, to identify and prevent asthma triggers, and to create response plans to treat asthma flare-ups.
At Children’s Hospital of Michigan, our Immunodeficiency Clinic provides diagnostic and treatment services for children and adults with suspected or known as inborn error of immunity (IEI). We serve as a referral center to help families and physicians in the evaluation and care of individuals with immunodeficiency disorders. Our program is the only coordinating center for the State of Michigan Newborn Screening Program for Severe Combined Immunodeficiency. One of three management centers in the state. Our multidisciplinary team includes a clinical immunologist, immunology nurse educator, and social worker, and offers comprehensive medical and psychosocial support and resources to patients with immunodeficiency and their families. We work closely with infectious disease specialists and Hematology/Oncology Transplant medicine specialists to provide access to the latest treatment options. Our program is a member of the United States Immunodeficiency Network (USIDNET) and Immunodeficiency Foundation (IDF). We welcome the opportunity to provide a second opinion on the diagnosis and/or treatment plan for inborn error of immunity.
Systemic vasculitis in children is a complex group of diseases affecting multiple organ systems. Comprehensive care may require coordinated treatment across multiple specialties including pediatric rheumatology and pediatric nephrology. The Vasculitis Clinic at Children’s Hospital of Michigan is a cooperative effort of physicians to allow the patient to see both specialists in a single visit for ease of collaboration onsite, and to form a care plan that encompasses all aspects of this complex group of diseases.
Pediatric Autoinflammatory Clinic
– Focus: rare genetic immune disorders with recurrent, unprovoked inflammation
– Collaborative care: immunology + pediatric rheumatology
Appointments with the Allergy, Asthma and Immunology experts are available at five convenient Children’s Hospital of Michigan locations throughout the metropolitan area listed below. Pediatric Rheumatology appointments are available at Children’s Hospital of Michigan Specialty Center – Detroit and Troy location. Families can call 313-745-KIDS or 313-832-8550 to schedule an appointment.
Our Team is Dedicated to You
Allergy Immunology Rheumatology Attendings
Learn about our University Pediatricians Attendings
Advanced Practice Providers
Want to learn more about our distinguished specialists? Click the button below to be taken to our Faculty Directory.
Education
At the Children’s Hospital of Michigan, our goals are to prepare our fellows to pursue future careers in academic medicine or subspecialty clinical practice and to qualify for the American Board of Allergy and Immunology.
The program is ACGME accredited and offers comprehensive, balanced clinical training in allergy/immunology in both adults and pediatric patients, with emphasis on evaluation and management of allergic disorders, asthma and primary immunodeficiency disorders. We prepare our fellows for a strong foundation in the basic and clinical immunology important to understanding and managing allergic/immunologic disorders.
The institution is a major pediatric tertiary referral center and is the coordinating center for the Severe Combined Immune Deficiency Newborn Screening Program for the State of Michigan. Fellows gain additional experience in dedicated clinics for inner-city asthma, eosinophilic esophagitis, and primary immunodeficiency disorders with specialized nursing staff and social workers. Elective rotations in ENT, dermatology, rheumatology, pulmonology, and infectious disease are available in both adult and pediatric specialties. Other elective rotations include clinical immunology laboratory and allergen extract preparation. Fellows will be proficient in allergen immunotherapy, monoclonal antibody treatments, immunoglobulin replacement therapy, and other treatment modalities available for primary immunodeficiency disorders.
Fellows will learn to design and conduct allergy and/or immunology research under the supervision of research mentor(s) who are fellowship program faculty. Research resources are available through the Children’s Research Institute of Michigan and the Children’s Hospital Foundation. Fellow research projects are involved in QI, translational, and clinical research. Fellows are expected to present their research at national meetings and in peer-reviewed publications.
For more information, please refer to the Allergy/Immunology Fellowship Training Website—click here or on the button below to visit the site.
About our Fellowship Offerings
Trainees Accepted Each Year: 2 per year
Duration of Fellowship: 2 years
Number of Graduates Last 5 Years, and Subsequent Career Choice: 2018-2023 8 graduates (5 academic, 3 private practice)
Application Deadline: Please refer to the National Resident Matching Program (NRMP) website for fellowship match information in regards to the fellowship timeline, application deadlines and additional important dates.
Electives for Residents and Students: Yes
Special Requirements: ABIM or ABP eligible or certified
Division of Allergy, Immunology, and Rheumatology
Children’s Hospital of Michigan
3950 Beaubien Blvd.
Detroit, MI 48201
Phone: (313) 745-5751 and (313) 832-8506
Fax: (313) 993-7118
Email: ppoowutt@dmc.org
Program Website: https://www.childrensdmc.org/health-professionals/just-for-doctors/fellowships/allergy-immunology
Program Director
Pavadee Poowuttikul, MD
Phone: (313) 745-5751, (313) 832-8506
Email: ppoowutt@dmc.org
Associate Program Director
Dr. Aishwarya Navalpakam
Program Coordinator
Dionne Weathers
Pediatric Graduate Medical Education
Phone: 313-745-5751
313-832-8506 Specialty Center
Email: Dweather@dmc.org
Fax: 313-993-7118
Research
Our faculty and fellows are committed to research involving the diagnosis and management of patients with inner-city asthma, primary and secondary immunodeficiency diseases, autoimmune, rheumatologic, and other immunologic diseases, food allergies and other atopic disorders through basic, translational, and clinical research.
Our active clinical research trials/projects include:
The Use of an Electronic Monitoring Device for Wheezing (Wheezo) and a Remote Monitoring Program (RMP) to Improve Asthma Outcomes in Inner-City Children
Extent of Immunosuppression from Oral Steroid Bursts in Inner-City Asthma Children
The Evaluation of Treatment and Outcomes in Patients with Eosinophilic Esophagitis
Clinical Markers for Likelihood of Admission to Pediatric Intensive care unit (PICU) due to Anaphylaxis
Anaphylaxis and Asthma Education in Schools
Predictors for Low TRECs in infants without SCID or severe thymic defects
Outcomes of TREC based SCID Newborn Screening in Michigan: 10-year data
Geomapping High-Risk Zip codes in Detroit for social determinants of health
Risk Factors Associated with Poor Asthma Control Utilizing National Dataset
A Randomized, Double-blind, Multicenter, Parallel-group, Phase IIIb 52 Week Study Evaluating the Efficacy and Safety of PT027 Compared with PT007 Administered As Needed in Participants 12 to < 18 Years of Age with Asthma (ACADIA)
A Validation Study of the Pediatric Asthma Impairment and Risk Questionnaire (AIRQ)
A Multicentre, Randomized, Double-Blind, Parallel-Group Placebo-Controlled, Phase 3, Efficacy and Safety Study of Tezepelumab in 5 to <12 Year Old Children with Severe Uncontrolled Asthma (HORIZON)
Penicillin de-labeling program
Asthma in-patient discharge quality improvement project
Evaluation for post-transplant secondary immunodeficiency
Evaluation for secondary immunodeficiency with immunosuppressive medications
The Impact of Food Insecurity in Food Allergic Populations
Inpatient community health worker program for poorly controlled pediatric asthma
Clinical Trial:
52-week, multicenter, randomized, double-blind, placebo-controlled study of remibrutinib (LOU064) for IgE-mediated food allergy (adults and adolescents)
Recent Publications and Recent Areas of Focus
Marwa El-Bohy
El-Bohy M, Poowuttikul P, Secord E. Humoral Immune Deficiencies of Childhood. Immunol Allergy Clin North Am. 2021 Nov;41(4):527-533. doi: 10.1016/j.iac.2021.07.004. PMID: 34602225.
El-Bohy M, Poowuttikul P, Secord E. Humoral Immune Deficiencies of Childhood. Pediatr Clin North Am. 2019 Oct;66(5):897-903. doi: 10.1016/j.pcl.2019.06.010. PMID: 31466679.
Basil Fathalla, MD
Fathalla BM, Elgabaly EA, Tayoun AA. Coexistence of a novel WISP3 pathogenic variant and an MEFV mutation in an Arabic family with progressive pseudorheumatoid dysplasia mimicking polyarticular juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2020 Sep 7;18(1):69.
Kashyape P, D’Souza AP, Fathalla B. En coup de sabre presenting as status epilepticus. Clin Rheumatol. 2020 Dec; 39(12):3885-3886.
Mathew A, Abuhammour W, Fathalla B, Otour B. Parvovirus B19 Infection Mimicking Juvenile Myelomonocytic Leukemia in an Immunocompetent Child. Cureus. 2020 Jun 26;12(6):e8854.
Mahfouz NA, Kizhakkedath P, Ibrahim A, El Naofal M, Ramaswamy S, Harilal D, Qutub Y, Uddin M, Taylor A, Alloub Z, AlBanna A, Abuhammour W, Fathalla B, Tayoun AA. Utility of clinical exome sequencing in a complex Emirati pediatric cohort. Comput Struct Biotechnol J. 2020 Apr 22;18:1020-1027.
Al-Mayouf SM, Almutairi A, Albrawi S, Fathalla BM, Alzyoud R, AlEnazi A, Abu-Shukair M, Alwahadneh A, Alsonbul A, Zlenti M, Khawaja E, Abushhaiwia A, Khawaja K, AlMosawi Z, Madan W, Almuatiri M, Almuatiri N; for Pediatric Arab Rheumatology Group (PRAG). Pattern and diagnostic evaluation of systemic autoinflammatory diseases other than familial Mediterranean fever among Arab children: a multicenter study from the Pediatric Rheumatology Arab Group (PRAG). Rheumatol Int. 2020 Jan;40(1):49-56.
Jenny Huang, MD
Huang J, Shankar A, Hurden I, et al. Increased mortality in infants with abnormal T-cell receptor excision circles. Pediatr Res. Published online March 5, 2024. doi:10.1038/s41390-024-03121-7
Mongkonsritragoon, W, Huang, J, Fredrickson, M, Seth, D, Poowuttikul, P. Positive Newborn Screening for Severe Combined Immunodeficiency: What Should the Pediatrician Do?. Clin Med Insights Pediatr. 2023; 17. 37025258. 10.1177/11795565231162839
Mongkonsritragoon, W, Prueksapraoprong, C, Kewcharoen, J, Tokavanich, N, Prasitlumkum, N, Huang, J, Poowuttikul, P. Prevalence and risk associated with asthma in children hospitalized with SARS-CoV-2: a meta-analysis and systematic review. J Allergy Clin Immunol Pract. 2022; 10(5): 1382-1384.e1. 35123100. 10.1016/j.jaip.2021.12.044
Huang J, Kaur B, Farooqi A, et al. Elevated Glycated Hemoglobin Is Associated with Reduced Antibody Responses to Vaccinations in Children. Pediatr Allergy Immunol Pulmonol. 2020;33(4):193-198. doi:10.1089/ped.2020.1160
Aishwarya Navalpakam
Navalpakam A, Thanaputkaiporn N, Aijja C, et al. Impact of steroids on the immune profiles of children with asthma living in the inner-city. Allergy Asthma Proc. 2024;45(2):100-107. doi:10.2500/aap.2024.45.230090
Navalpakam A, Thanaputkaiporn N, Poowuttikul P. Anaphylaxis: Long-term management and resources. Allergy Asthma Proc. 2023;44(1):35-44. doi:10.2500/aap.2023.44.220089
Mongkonsritragoon W, Srivastava R, Seth D, Navalpakam A, Poowuttikul P. Non-infectious Pulmonary Complications in Children with Primary Immunodeficiency. Clin Med Insights Pediatr. 2023;17:11795565231196431. Published 2023 Sep 8. doi:10.1177/11795565231196431
Navalpakam A, Thanaputkaiporn N, Poowuttikul P. Management of Anaphylaxis. Immunol Allergy Clin North Am. 2022;42(1):65-76. doi:10.1016/j.iac.2021.09.005
Navalpakam A, Secord E, Pansare M. The Impact of Coronavirus Disease 2019 on Pediatric Asthma in the United States. Pediatr Clin North Am. 2021;68(5):1119-1131. doi:10.1016/j.pcl.2021.05.012
Milind Pansare, MD
Alrayes T, Shihan H, Smith-Dewey R, et al. Enlarging Nasal Cavity Mass in a Young Adolescent Male. Clin Pediatr (Phila). 2023;62(1):68-72. doi:10.1177/00099228221110957
Pansare M, Seth D, Kamat A, Kamat D. Summer Buzz: All You Need to Know about Insect Sting Allergies. Pediatrics in Review, Jul 2020, 41 (7) 348-356
Saini S, Pansare M. New Insights and Treatments in Atopic Dermatitis. Immunol Allergy Clin North Am. 2021;41(4):653-665. doi:10.1016/j.iac.2021.07.005
Pavadee Poowuttikul, MD
Navalpakam A, Thanaputkaiporn N, Aijja C, et al. Impact of steroids on the immune profiles of children with asthma living in the inner-city. Allergy Asthma Proc. 2024;45(2):100-107. doi:10.2500/aap.2024.45.230090
Navalpakam A, Thanaputkaiporn N, Poowuttikul P. Anaphylaxis: Long-term management and resources. Allergy Asthma Proc. 2023;44(1):35-44. doi:10.2500/aap.2023.44.220089
Mongkonsritragoon, W., Prueksapraoprong, C., Kewcharoen, J., Tokavanich, N., Prasitlumkum, N., Huang, J., Poowuttikul, P. Prevalence and Risk associated with Asthma in Children hospitalized with SARS-CoV-2: A Meta-analysis and Systematic review. [published online ahead of print, 2022 Feb 2]. J Allergy Clin Immunol Pract. 2022 May;10(5):1382-1384.e1. doi: 10.1016/j.jaip.2021.12.044. Epub 2022 Feb 2.
Secord, E., Poowuttikul, P., Hoofman, J., Arsenault, S. Sustained Decrease in Pediatric Asthma Emergency Visits During the First Year of COVID-19 Pandemic. Allergy Asthma Proc. 2021;42(5):400-402. doi:10.2500/aap.2021.42.210059
Alvarez, A., Gupta, M., Poowuttikul, P., Baptist, A. Are primary care physicians following National Institute of Allergy and Infectious Disease guidelines for the prevention of peanut allergy? A survey-based study. Allergy Asthma Proc. 2020 May 1;41(3):167-171. doi: 10.2500/aap.2020.41.200019. PMID: 32375960
Darian, T., Freij, J., Seth, D., Poowuttikul, P., Secord, E. A Review of Primary Immune Deficiency Disorders. EMJ Allergy Immunol. 2020;5[1]:70-77.
Poowuttikul, P., Seth, D. New Concepts and Technological Resources in Patient Education and Asthma Self-Management. Clin Rev Allergy Immunol. 2020 Mar 25. doi: 10.1007/s12016-020-08782-w. Review. PMID: 32215784
Huang J, Kaur B, Farooqi A, et al. Elevated Glycated Hemoglobin Is Associated with Reduced Antibody Responses to Vaccinations in Children. Pediatr Allergy Immunol Pulmonol. 2020;33(4):193-198. doi:10.1089/ped.2020.1160
Seth, D., Poowuttikul, P., Pansare, M., Kamat, D. Food Allergy: A Review. Pediatr Ann. 2020;49(1):e50-e58. doi:10.3928/19382359-20191206-01. PMID: 31930423
Divya Seth, MD
Huang J, Shankar A, Hurden I, Thomas R, Hill J, Seth D, Secord E, Poowuttikul P. Increased mortality in infants with abnormal T-cell receptor excision circles. Pediatr Res. Published online March 5, 2024. doi:10.1038/s41390-024-03121-7
Mongkonsritragoon W, Srivastava R, Seth D, Navalpakam A, Poowuttikul P. Non-infectious Pulmonary Complications in Children with Primary Immunodeficiency. Clin Med Insights Pediatr. 2023;17:11795565231196431. Published 2023 Sep 8. doi:10.1177/11795565231196431
Seth D, Poowutikul P, Pansare M, Kamat D. Food Allergy: A Review. Pediatr Ann. 2020; 49(1):e50-e58. PMID: 31930423.
Poowuttikul P, Seth D. New Concepts and Technological Resources in Patient Education and Asthma Self-Management. Clinical Reviews in Allergy & Immunology 2020; 59(1):19-37
Darian T, Freij JB, Seth D, Poowuttikul P, Secord E. EMJ Allergy Immunol. 2020; 5(1): 70-77.
Pansare M, Seth D, Kamat A, Kamat D. Summer buzz: All you need to know about insect sting allergies. Pediatrics In review. July 2020; 41(7): 348-356.
Huang, Jenny; Kaur, Bani; Farooqi, Ahmad; Miah, Tayaba; McGrath, Eric; Seth, Divya; Secord, Elizabeth; Poowuttikul, Pavadee. Elevated Glycated Hemoglobin Is Associated with Reduced Antibody Responses to Vaccinations in Children. Pediatr Allergy Immunol Pulmonol. 2020;33(4):193-198. doi:10.1089/ped.2020.1160
Veronica Kwiatkowski
Kwiatkowski V, A. Navalpakam , P. Poowuttikul. Idiopathic Hypereosinophilic Syndrome Diagnosed in an Infant: A Case Report. https://www.annallergy.org/article/S1081-1206(22)01543-5/fulltext
Kwiatkowski V, Narin Thanaputkaiporn, Pavadee Poowuttikul, MD, MD FAAAAI, NFKB2 Mutation in 2 Siblings with DAVID Syndrome and CVID with Variable Presentation. https://www.jacionline.org/article/S0091-6749(21)01946-1/fulltext
Kwiatkowski V, Abigail I. Franco, Maria R. Cordisco, Craig A. Mullen. A rapidly-changing skin lesion in an 11-year-old boy https://publications.aap.org/pediatricsinreview/article-abstract/44/2/96/190487/A-Rapidly-Changing-Skin-Lesion-in-an-11-year-old?redirectedFrom=PDF
Sean M Frey , Nicolas P N Goldstein, Kwiatkowski V, Ariel Reinish. Clinical outcomes for young children diagnosed with asthma versus reactive airway disease https://pubmed.ncbi.nlm.nih.gov/34153535/
Kwiatkowski V, J. Lomas. Positive skin testing to mold in patients with allergic reactions to preservative-free juices https://www.annallergy.org/article/S1081-1206(20)30782-1/abstract
Kwiatkowski V, J. Lomas. Prevalence of previous tonsillectomy in pediatric patients with eosinophilic esophagitis https://www.annallergy.org/article/S1081-1206(20)30721-3/abstract
Kwiatkowski V, Franco AI, Cordisco MR, Mullen CA. A Rapidly Changing Skin Lesion in an 11-year-old Boy. Pediatr Rev. 2023;44(2):96-99. doi:10.1542/pir.2020-004671
Frey SM, Goldstein NPN, Kwiatkowski V, Reinish A. Clinical Outcomes for Young Children Diagnosed With Asthma Versus Reactive Airway Disease. Acad Pediatr. 2022;22(1):37-46. doi:10.1016/j.acap.2021.06.009
Basil Fathalla, MD
Fathalla BM. Clinical Manifestations and MEFV mutations in Children with Familial Mediterranean Fever living in Southeast Michigan. Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID). Toronto, 2023.
Banisad E, Benchaala I, Lin X, Fathalla BM. Three Generations with Blau Syndrome: Clinical Course and Outcome of the Timely Treated, Partially Treated, and the Untreated. Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID). Toronto, 2023
Maggi RB, Jain A, Fathalla BM. Variable Clinical Phenotypes in Siblings with the same DNASE1L3 Pathogenic Genotype: A Case Report of a Rare form of Monogenic Lupus.Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID). Toronto, 2023.
Al-Antary E, Arar R, Gallardo M, Persaud Y, Fathalla B, Rajpurkar M, Bhambhani K. Unusual Presentation of TTP in a Newly Diagnosed Patient with SLE in the Setting of COVID 19. ASPHO (The American Society of Pediatric Hematology / Oncology) Conference, 2021
Jenny Huang, MD
Troy, A, Huang, N, Ajja, C, Pansare, M, Poowuttikul, P, Thomas, R, Huang, J. Risk Factors for Poor Asthma Control in an Urban Pediatric Population During the COVID-19 Pandemic. Journal of Allergy and Clinical Immunology, 2023
Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021
Aishwarya Navalpakam
Thanaputkaiporn,Narin, Mongkonsritragoon, Wimwipa, Navalpakam, Aishwarya, Poowuttikul, Pavadee. The Use of Picture-based Asthma Action Plan to Improve Asthma care in Inner City Children. Pediatric Academic Society, 2023.
Yamak O, Kwiatkowski V, Navalpakam A, Poowuttikul P. IL6ST Hyper IgE Syndrome: Three Family Members with Identical Mutations and Variable Presentations. Journal of Allergy and ClinicalImmunology, 2023
Kwiatkowski V, Navalpakam A, Poowuttikul P. Idiopathic Hypereosinophilic Syndrome Diagnosed in an Infant: A Case Report. Annals of Allergy, Asthma and Immunology, 2022
Yamak O, Navalpakam A, Poowuttikul P. A Unique Presentation of GATA2 Deficiency, Emberger Syndrome. Annals of Allergy, Asthma and Immunology, 2022.
Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021
Navalpakam A, Saini S, Seth D, Huang J, Poowuttikul P. A Quality Improvement Initiative to Improve Resident- Physician Practices Regarding Flu Vaccine Administration in Individuals with Egg Allergy. Journal of Allergy and Clinical Immunology, 2021
Milind Pansare, MD
Troy, A, Huang, N, Ajja, C, Pansare, M, Poowuttikul, P, Thomas, R, Huang, J. Risk Factors for Poor Asthma Control in an Urban Pediatric Population During the COVID-19 Pandemic. Journal of Allergy and Clinical Immunology, 2023
Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021
E Secord, P Poowuttikul, M Pansare, D Seth, S Saini. Pediatric Emergency Visits for Asthma Drop Significantly with COVID19 School Closure. Journal of Allergy and Clinical Immunology, 2021
Pavadee Poowuttikul, MD
Yamak O, Kwiatkowski V, Navalpakam A, Poowuttikul P. IL6ST Hyper IgE Syndrome: Three Family Members with Identical Mutations and Variable Presentations. Journal of Allergy and ClinicalImmunology, 2023
Troy, A, Huang, N, Ajja, C, Pansare, M, Poowuttikul, P, Thomas, R, Huang, J. Risk Factors for Poor Asthma Control in an Urban Pediatric Population During the COVID-19 Pandemic. Journal of Allergy and Clinical Immunology, 2023
Kwiatkowski V, Navalpakam A, Poowuttikul P. Idiopathic Hypereosinophilic Syndrome Diagnosed in an Infant: A Case Report. Annals of Allergy, Asthma and Immunology, 2022
Yamak O, Navalpakam A, Poowuttikul P. A Unique Presentation of GATA2 Deficiency, Emberger Syndrome. Annals of Allergy, Asthma and Immunology, 2022.
Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021
Kwiatkowski V, Thanaputkaiporn N, Poowuttikul P. NFKB2 Mutation in 2 Siblings with DAVID syndrome and CVID with Variable Presentations. Journal of Allergy and Clinical Immunology, 2022.
Navalpakam A, Saini S, Seth D, Huang J, Poowuttikul P. A Quality Improvement Initiative to Improve Resident- Physician Practices Regarding Flu Vaccine Administration in Individuals with Egg Allergy. Journal of Allergy and Clinical Immunology, 2021
Saini S, Navalpakam A, Seth D, Huang J, Poowuttikul P. Quality Improvement Initiative to Improve Resident-Physician Practices Regarding Peanut Introduction in Infancy. Journal of Allergy and Clinical Immunology, 2021
E Secord, P Poowuttikul, M Pansare, D Seth, S Saini. Pediatric Emergency Visits for Asthma Drop Significantly with COVID19 School Closure. Journal of Allergy and Clinical Immunology, 2021
Divya Seth, MD
Seth D, Nyenhuis SM, Pappalardo AA. Factors Affecting Adaptation of the AAAAI Picture-based Asthma Action Plan: a Survey-Based Study, 2022
Navalpakam, A. Thanaputkaiporn, N, Ajja, C, Farooqi, A, Pansare, M, Seth, D, Huang, J, Poowuttikul, P. Immune Profiles in Inner-city Asthmatic Children Receiving Frequent Systemic Steroids. Journal of Allergy and Clinical Immunology, 2021
Navalpakam A, Saini S, Seth D, Huang J, Poowuttikul P. A Quality Improvement Initiative to Improve Resident- Physician Practices Regarding Flu Vaccine Administration in Individuals with Egg Allergy. Journal of Allergy and Clinical Immunology, 2021
Saini S, Navalpakam A, Seth D, Huang J, Poowuttikul P. Quality Improvement Initiative to Improve Resident-Physician Practices Regarding Peanut Introduction in Infancy. Journal of Allergy and Clinical Immunology, 2021
Pavadee Poowuttikul, MD
Role: Grant Director, Percent Effort: 35%
Title: “Primary Immunodeficiencies Coordinating Center for Severe Combined Immunodeficiency Newborn Screening Program” Source: Michigan Department of Community Health-SCID NBS
Total Period of Support: 1 year 10/2020-09/2021
Role: PI, Percent Effort: 10% (no salary support)
Title: “Immunosuppression from Systemic Steroid Bursts in Asthma” Source: Children’s Hospital of Michigan Foundation R1-2020-78
Total Period of Support: 2 year 01/2020-12/2021
Role: PI, Percent Effort: 10% (no salary support)
Title: “Picture-based Asthma Action Plan” Source: American Academy of Allergy, Asthma and Immunology (AAAAI)
Total Period of Support: 3 year 11/2017-11/2020
Jenny Huang, MD
Awards:
Resident Teaching Award. Children’s Hospital of Michigan
Wolf W. Zuelzer Fellow Research Award Finalist Competition – Third place
Milind Pansare, MD
Other Professional Accomplishments:
Manuscript reviewer for Annals of Allergy, Asthma and Immunology. Reviewed 5 manuscripts in year 2020.
Abstract reviewer for American Academy of Asthma, Allergy and Immunology (AAAAI).6 abstracts in year 2020.
Group leader for In-Training Examination committee-Wrote and reviewed in-training examination questions(Total-50Q) for fellows-in-training. Oct 2020 to Dec 2020.
Faculty and Mentor in the 2020 Online Workshop (July 13th – August 8th)
In Global Health Research & Fieldwork Practices organized by the Global Health Research Collaborative & the Wayne State University School of Medicine. Lead a group discussion on pediatric anaphylaxis and areas of research Mentor/Advise-latex allergy for researcher from Central America
Pavadee Poowuttikul, MD
Awards:
Hour Magazine “Top Doc” 2020
Other Professional Accomplishments:
American Academy of Allergy, Asthma and Immunology (AAAAI) Office of School-based Management of Asthma Taskforce
American Academy of Allergy, Asthma and Immunology (AAAAI) Primary Immunodeficiency Diseases Committee
American Academy of Allergy, Asthma and Immunology (AAAAI) Fellow-In-Training Examination Committee
American Academy of Allergy, Asthma and Immunology (AAAAI) Health Informatics, Technology & Education (HITE) Committee
Divya Seth, MD
Other Professional Accomplishments:
Approved for Fellow status in American Academy of Allergy, Asthma and Immunology (AAAAI)-March 2020
Aishwarya Navalpakam
Awards:
Journeys & Frontiers in Pediatric Research Program Awardee
AAAAI Leadership Institute Mentorship Program Awardee: Leadership project – Survey project regarding climate change curriculum in Allergy/Immunology fellowship
Wolf W. Zuelzer Fellow Research Award Recipient, First Place
Other Professional Accomplishments:
Vice Chair of the Bylaw Review Committee for CMUCOM
Basil Fathalla, MD
Awards:
Associate Professor Teacher of the Year Award, Children’s Hospital of Michigan / DMC Pediatric Residency Program
TOP DOCS’ Hour Detroit Magazine
Other Professional Accomplishments:
Founder, Founding member of Pediatric Rheumatology Arab Group-PRAG a subgroup of ARLAR (Arab League Against Rheumatism)
Advocacy & Other Special Areas of Focus
Our faculty are committee members in the American Academy of Allergy, Asthma, and Immunology (AAAAI), American College of Allergy, Asthma and Immunology (ACAAI), American Board of Allergy and Immunology (ABAI)
AAAAI Leadership Institute
Leadership project with AAAAI Website, Internet, and Related Technologies (WIRT) to lead an innovative project on implementing picture-based asthma action plan for AAAAI and School-based Asthma Management Program.
AAAAI Committee on the Underserved with an interest in food insecurity and patients living in inner-city with food allergies.
Women’s Health in Allergy/Immunology: with an interest in creating educational modules for health care providers caring for pregnant people with asthma
Fellow-In-Training Examination Committee: 2 of our faculty members were selected to write questions for the Fellow-In-Training Examination questions
Test Writing Committee of the ABAI: one of our faculty members was selected to write questions for the ABAI
One of our faculty members was selected to be an ABAI ambassador
Central Michigan University College of Medicine (CMUCOM)
Our faculty members are involved in the Central Michigan University College of Medicine (CMUCOM) and Children’s Hospital of Michigan committees including:
One of our faculty members is the Vice Chair of the Bylaw Review Committee for CMUCOM
One of our faculty members is on Central Michigan University Pediatric Department’s Academic Promotion Committee and the University Pediatricians Advisory Board
The Division participates in the American College of Allergy, Asthma and Immunology Asthma (ACAAI) Screening Camp.
Immune Deficiency Foundation (IDF)
We also participate in the Immune Deficiency Foundation (IDF) activities, including organizing IDF walk yearly in Detroit, Michigan. IDF is a non-profit organization that seeks to improve diagnosis, treatment, and quality of life for people with primary immune deficiency (PID) by fostering a community empowered by advocacy, education, and research. The IDF achieves their goals as a resource for education materials, publications, conferences, provider referrals, research, public policy advocacy, and through health care provider education. The IDF walk is a community event that supports and connects the PID community and also is a major fundraiser to support the mission of the IDF. Our staff coordinated and held the walk on our campus beginning in 2018. We started as a local walk and are now recognized as a national walk site. Our Immunology nurse serves on the Nurse Advisory Committee of the IDF.
IDF/United States Immunodeficiency Network (USIDNET)
The Division also participates in the IDF/United States Immunodeficiency Network (USIDNET) registry. The USIDNET is a research consortium established to advance scientific research in the field of primary immunodeficiency diseases with current focus on the primary immunodeficiency disease registry, education and mentoring for young investigators. The USIDNET registry is a national patient consented registry for individuals with primary immunodeficiency diseases. The goals are to advance research in the field and to improve the quality of life of patients. It is managed by leading immunologists and administered by the Immune Deficiency Foundation (IDF). Our faculty and nurses have enrolled patients into the USIDNET/FILL registry, have supported registry development, and the Children’s Hospital of Michigan was the first enrolling site in Michigan. Our faculty serves on the Severe Combined Immunodeficiency Disease specific work group of the USIDNET – IDF.